1 Ocak 2018 Dergi makalesi Açık Erişim

Kilic, Sevgi

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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Kilic, Sevgi</dc:creator>
  <dc:date>2018-01-01</dc:date>
  <dc:description>Mixtures of 1,2 Distearoyl-sn-glycero-3-phosphocholine (DSPC) and polyoxyethylene-40-stearate (PEG(40)St) were prepared at different molar ratios and their miscibility were investigated using Langmuir isotherms. Pure DSPC monolayer exhibited a liquid-condensed (LC) phase whereas PEG(40)St monolayer exhibited liquid-expanded (LE) phase at the air-water interface at 22 +/- 2 degrees C. At the collapse pressure of 33 mN/m, the PEG(40)St mean molecular area was calculated to be 28 angstrom(2)/molecule for 9: 1 composition and 50 angstrom(2)/molecule for 5: 5 composition, showing an increasing trend with the emulsifier content. A quantification method was developed to estimate the squeeze out amount of PEG(40)St from Langmuir isotherms of the DSPC/PEG(40)St mixtures at different molar ratios. Almost 93%, 82%, and 53% of PEG(40)St displaced for the 9:1, 7:3, and 5:5 mixtures, respectively, at the end of the first collapse plateau and showed a decreasing trend with the PEG(40)St content. Remaining PEG(40)St squeezed out at the end of the second collapse plateau, where 20% of PEG(40)St still contained within the 5: 5 composition. It was concluded that increasing PEG(40)St content would be advantageous to design more stable lipid based microbubbles.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/28691</dc:identifier>
  <dc:identifier>oai:zenodo.org:28691</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 551 58-64</dc:source>
  <dc:title>Quantification of PEG(40)St squeeze out from DSPC/PEG(40)St monolayers at higher molar ratios</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
</oai_dc:dc>