Dergi makalesi Açık Erişim
Kilic, Sevgi
<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd"> <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/28691</identifier> <creators> <creator> <creatorName>Kilic, Sevgi</creatorName> <givenName>Sevgi</givenName> <familyName>Kilic</familyName> <affiliation>Izmir Inst Technol, Dept Chem Engn, TR-35430 Izmir, Turkey</affiliation> </creator> </creators> <titles> <title>Quantification Of Peg(40)St Squeeze Out From Dspc/Peg(40)St Monolayers At Higher Molar Ratios</title> </titles> <publisher>Aperta</publisher> <publicationYear>2018</publicationYear> <dates> <date dateType="Issued">2018-01-01</date> </dates> <resourceType resourceTypeGeneral="Text">Journal article</resourceType> <alternateIdentifiers> <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/28691</alternateIdentifier> </alternateIdentifiers> <relatedIdentifiers> <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.colsurfa.2018.05.001</relatedIdentifier> </relatedIdentifiers> <rightsList> <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights> <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights> </rightsList> <descriptions> <description descriptionType="Abstract">Mixtures of 1,2 Distearoyl-sn-glycero-3-phosphocholine (DSPC) and polyoxyethylene-40-stearate (PEG(40)St) were prepared at different molar ratios and their miscibility were investigated using Langmuir isotherms. Pure DSPC monolayer exhibited a liquid-condensed (LC) phase whereas PEG(40)St monolayer exhibited liquid-expanded (LE) phase at the air-water interface at 22 +/- 2 degrees C. At the collapse pressure of 33 mN/m, the PEG(40)St mean molecular area was calculated to be 28 angstrom(2)/molecule for 9: 1 composition and 50 angstrom(2)/molecule for 5: 5 composition, showing an increasing trend with the emulsifier content. A quantification method was developed to estimate the squeeze out amount of PEG(40)St from Langmuir isotherms of the DSPC/PEG(40)St mixtures at different molar ratios. Almost 93%, 82%, and 53% of PEG(40)St displaced for the 9:1, 7:3, and 5:5 mixtures, respectively, at the end of the first collapse plateau and showed a decreasing trend with the PEG(40)St content. Remaining PEG(40)St squeezed out at the end of the second collapse plateau, where 20% of PEG(40)St still contained within the 5: 5 composition. It was concluded that increasing PEG(40)St content would be advantageous to design more stable lipid based microbubbles.</description> </descriptions> </resource>
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