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Cytotoxicity of Natural Compounds Isolated from the Seeds of Garcinia afzelii

Lannang, Alain Meli; Louh, Gabin Nselapi; Biloa, Bernadette Messi; Komguem, Justin; Mbazoa, Celine Djama; Sondengam, Beiban Luc; Naesens, Lieve; Pannecouque, Christophe; De Clercq, Erik; El Ashry, El Sayed H.


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      {
        "name": "Lannang, Alain Meli"
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      {
        "affiliation": "Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon", 
        "name": "Louh, Gabin Nselapi"
      }, 
      {
        "affiliation": "Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon", 
        "name": "Biloa, Bernadette Messi"
      }, 
      {
        "affiliation": "Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon", 
        "name": "Komguem, Justin"
      }, 
      {
        "affiliation": "Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon", 
        "name": "Mbazoa, Celine Djama"
      }, 
      {
        "affiliation": "Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon", 
        "name": "Sondengam, Beiban Luc"
      }, 
      {
        "affiliation": "Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium", 
        "name": "Naesens, Lieve"
      }, 
      {
        "affiliation": "Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium", 
        "name": "Pannecouque, Christophe"
      }, 
      {
        "affiliation": "Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium", 
        "name": "De Clercq, Erik"
      }, 
      {
        "affiliation": "Univ Alexandria, Dept Chem, Fac Sci, Alexandria 21321, Egypt", 
        "name": "El Ashry, El Sayed H."
      }
    ], 
    "description": "The new compounds guttiferone O (1) and 3-methoxycheffouxanthone (2) have been isolated from the seeds of Garcinia afzelii Engl., together with nine known compounds: 2-hydroxy-1,7-dimethoxyxanthone (3), smeathxanthone A (4), 1,5-dihydroxyxanthone (5), 1,6-dihydroxy-5-methoxyxanthone (6), cheffouxanthone (7), 1,3,5-trihydroxyxanthone (8), smeathxanthone B (9), isoxanthochymol (10) and guttiferone E (11). Their structures were elucidated by means of 1D and 2D-NMR techniques. All the isolates showed high cytotoxic activity and were found inactive when tested against HIV and influenza viruses.", 
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      "issue": "7", 
      "pages": "708-712", 
      "title": "PLANTA MEDICA", 
      "volume": "76"
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      "title": "Dergi makalesi", 
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    "title": "Cytotoxicity of Natural Compounds Isolated from the Seeds of Garcinia afzelii"
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