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Cytotoxicity of Natural Compounds Isolated from the Seeds of Garcinia afzelii

Lannang, Alain Meli; Louh, Gabin Nselapi; Biloa, Bernadette Messi; Komguem, Justin; Mbazoa, Celine Djama; Sondengam, Beiban Luc; Naesens, Lieve; Pannecouque, Christophe; De Clercq, Erik; El Ashry, El Sayed H.


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/28339</identifier>
  <creators>
    <creator>
      <creatorName>Lannang, Alain Meli</creatorName>
      <givenName>Alain Meli</givenName>
      <familyName>Lannang</familyName>
    </creator>
    <creator>
      <creatorName>Louh, Gabin Nselapi</creatorName>
      <givenName>Gabin Nselapi</givenName>
      <familyName>Louh</familyName>
      <affiliation>Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon</affiliation>
    </creator>
    <creator>
      <creatorName>Biloa, Bernadette Messi</creatorName>
      <givenName>Bernadette Messi</givenName>
      <familyName>Biloa</familyName>
      <affiliation>Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon</affiliation>
    </creator>
    <creator>
      <creatorName>Komguem, Justin</creatorName>
      <givenName>Justin</givenName>
      <familyName>Komguem</familyName>
      <affiliation>Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon</affiliation>
    </creator>
    <creator>
      <creatorName>Mbazoa, Celine Djama</creatorName>
      <givenName>Celine Djama</givenName>
      <familyName>Mbazoa</familyName>
      <affiliation>Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon</affiliation>
    </creator>
    <creator>
      <creatorName>Sondengam, Beiban Luc</creatorName>
      <givenName>Beiban Luc</givenName>
      <familyName>Sondengam</familyName>
      <affiliation>Univ Yaounde I, Dept Organ Chem, Fac Sci, Yaounde, Cameroon</affiliation>
    </creator>
    <creator>
      <creatorName>Naesens, Lieve</creatorName>
      <givenName>Lieve</givenName>
      <familyName>Naesens</familyName>
      <affiliation>Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium</affiliation>
    </creator>
    <creator>
      <creatorName>Pannecouque, Christophe</creatorName>
      <givenName>Christophe</givenName>
      <familyName>Pannecouque</familyName>
      <affiliation>Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium</affiliation>
    </creator>
    <creator>
      <creatorName>De Clercq, Erik</creatorName>
      <givenName>Erik</givenName>
      <familyName>De Clercq</familyName>
      <affiliation>Katholieke Univ Leuven, Rega Inst Med Res, B-3000 Louvain, Belgium</affiliation>
    </creator>
    <creator>
      <creatorName>El Ashry, El Sayed H.</creatorName>
      <givenName>El Sayed H.</givenName>
      <familyName>El Ashry</familyName>
      <affiliation>Univ Alexandria, Dept Chem, Fac Sci, Alexandria 21321, Egypt</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Cytotoxicity Of Natural Compounds Isolated From The Seeds Of Garcinia Afzelii</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2010</publicationYear>
  <dates>
    <date dateType="Issued">2010-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/28339</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1055/s-0029-1240627</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The new compounds guttiferone O (1) and 3-methoxycheffouxanthone (2) have been isolated from the seeds of Garcinia afzelii Engl., together with nine known compounds: 2-hydroxy-1,7-dimethoxyxanthone (3), smeathxanthone A (4), 1,5-dihydroxyxanthone (5), 1,6-dihydroxy-5-methoxyxanthone (6), cheffouxanthone (7), 1,3,5-trihydroxyxanthone (8), smeathxanthone B (9), isoxanthochymol (10) and guttiferone E (11). Their structures were elucidated by means of 1D and 2D-NMR techniques. All the isolates showed high cytotoxic activity and were found inactive when tested against HIV and influenza viruses.</description>
  </descriptions>
</resource>
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