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Self-assembly of organocatalysts for the enantioselective Michael addition of aldehydes to nitroalkenes

Demir, Ayhan S.; Eymur, Serkan


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{
  "DOI": "10.1016/j.tetasy.2009.12.008", 
  "abstract": "A proline-thiourea self-assembled organocatalyst is described as a good catalyst for the enantioselective nitro-Michael addition of aldehydes to nitroalkenes The reaction is efficient with 5% of the thiourea, to give moderate to good enantioselectivity (up to 76% ee) High syn-selectivity was obtained with both branched and unbranched aliphatic aldehydes This is the first example of self-assembly of organocatalysts with an achiral additive in a Michael addition wherein aldehydes are utilized as donors. (c) 2009 Elsevier Ltd All rights reserved", 
  "author": [
    {
      "family": "Demir", 
      "given": " Ayhan S."
    }, 
    {
      "family": "Eymur", 
      "given": " Serkan"
    }
  ], 
  "container_title": "TETRAHEDRON-ASYMMETRY", 
  "id": "28275", 
  "issue": "1", 
  "issued": {
    "date-parts": [
      [
        2010, 
        1, 
        1
      ]
    ]
  }, 
  "page": "112-115", 
  "title": "Self-assembly of organocatalysts for the enantioselective Michael addition of aldehydes to nitroalkenes", 
  "type": "article-journal", 
  "volume": "21"
}
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