1 Ocak 2011 Dergi makalesi Açık Erişim

Ocak, Meltem; Helbok, Anna; von Guggenberg, Elisabeth; Ozsoy, Y.; Kabasakal, Levent; Kremser, Leopold; Decristoforo, Clemens

Citation Style Language JSON

{
  "DOI": "10.1016/j.nucmedbio.2010.07.009", 
  "abstract": "Introduction: Lack of correlation between in vitro and in vivo stability is a general problem for the development of radiopeptides especially in the case of minigastrin derivatives for therapeutic applications. In this study, we compared the influence of experimental conditions on radiopeptide stability results in vitro using a model Minigastrin (MG) analogue labelled with Lu-177. Additionally, we attempted to characterize the main serum enzymatic cleavage sites by matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry (MS) analysis.", 
  "author": [
    {
      "family": "Ocak", 
      "given": " Meltem"
    }, 
    {
      "family": "Helbok", 
      "given": " Anna"
    }, 
    {
      "family": "von Guggenberg", 
      "given": " Elisabeth"
    }, 
    {
      "family": "Ozsoy", 
      "given": " Y."
    }, 
    {
      "family": "Kabasakal", 
      "given": " Levent"
    }, 
    {
      "family": "Kremser", 
      "given": " Leopold"
    }, 
    {
      "family": "Decristoforo", 
      "given": " Clemens"
    }
  ], 
  "container_title": "NUCLEAR MEDICINE AND BIOLOGY", 
  "id": "19493", 
  "issue": "2", 
  "issued": {
    "date-parts": [
      [
        2011, 
        1, 
        1
      ]
    ]
  }, 
  "page": "171-179", 
  "title": "Influence of biological assay conditions on stability assessment of radiometal-labelled peptides exemplified using a Lu-177-DOTA-minigastrin derivative", 
  "type": "article-journal", 
  "volume": "38"
}