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Synthesis and asymmetric catalytic activity of (1S,1 ' S)-4,4 '-biquinazoline-based primary amines

Cakici, Murat; Catir, Mustafa; Karabuga, Semistan; Ulukanli, Sabri; Kilic, Hamdullah


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  <dc:creator>Cakici, Murat</dc:creator>
  <dc:creator>Catir, Mustafa</dc:creator>
  <dc:creator>Karabuga, Semistan</dc:creator>
  <dc:creator>Ulukanli, Sabri</dc:creator>
  <dc:creator>Kilic, Hamdullah</dc:creator>
  <dc:date>2011-01-01</dc:date>
  <dc:description>A series of (1S,1'S)-4,4'-biquinazoline-based primary amines were prepared from natural amino acids via a six-step reaction sequence of protection and condensation followed by key synthetic steps including chlorination, nickel(0)-mediated homocoupling, and deprotection. These novel amines were screened for the asymmetric ethylation of aryl aldehydes to yield alcohols with an (S)-configuration with enantiomeric excesses (ee) varying from 2% to 95%. (C) 2011 Elsevier Ltd. All rights reserved.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/18135</dc:identifier>
  <dc:identifier>oai:zenodo.org:18135</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>TETRAHEDRON-ASYMMETRY 22(3) 300-308</dc:source>
  <dc:title>Synthesis and asymmetric catalytic activity of (1S,1 ' S)-4,4 '-biquinazoline-based primary amines</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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