Dergi makalesi Açık Erişim
Bozaykut, Perinur; Sozen, Erdi; Kaga, Elif; Ece, Asli; Ozaltin, Esra; Ek, Bo; Ozer, Nesrin Kartal; Grune, Tilman; Bergquist, Jonas; Karademir, Betul
<?xml version='1.0' encoding='UTF-8'?> <record xmlns="http://www.loc.gov/MARC21/slim"> <leader>00000nam##2200000uu#4500</leader> <datafield tag="245" ind1=" " ind2=" "> <subfield code="a">The role of heat stress on the age related protein carbonylation</subfield> </datafield> <datafield tag="909" ind1="C" ind2="4"> <subfield code="p">JOURNAL OF PROTEOMICS</subfield> <subfield code="v">89</subfield> <subfield code="c">238-254</subfield> </datafield> <controlfield tag="001">15875</controlfield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="a">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="520" ind1=" " ind2=" "> <subfield code="a">Since the proteins are involved in many physiological processes in the organisms, modifications of proteins have important outcomes. Protein modifications are classified in several ways and oxidative stress related ones take a wide place. Aging is characterized by the accumulation of oxidized proteins and decreased degradation of these proteins. On the other hand protein turnover is an important regulatory mechanism for the control of protein homeostasis. Heat shock proteins are a highly conserved family of proteins in the various cells and organisms whose expressions are highly inducible during stress conditions. These proteins participate in protein assembly, trafficking, degradation and therefore play important role in protein turnover. Although the entire functions of each heat shock protein are still not completely investigated, these proteins have been implicated in the processes of protection and repair of stress-induced protein damage. This study has focused on the heat stress related carbonylated proteins, as a marker of oxidative protein modification, in young and senescent fibroblasts. The results are discussed with reference to potential involvement of induced heat shock proteins. This article is part of a Special Issue entitled: Protein Modifications.</subfield> </datafield> <datafield tag="650" ind1="1" ind2="7"> <subfield code="2">opendefinition.org</subfield> <subfield code="a">cc-by</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Marmara Univ, Dept Biochem, Fac Med, Genet & Metab Dis Res & Invest Ctr, TR-34668 Istanbul, Turkey</subfield> <subfield code="a">Sozen, Erdi</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Marmara Univ, Dept Biochem, Fac Med, Genet & Metab Dis Res & Invest Ctr, TR-34668 Istanbul, Turkey</subfield> <subfield code="a">Kaga, Elif</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Marmara Univ, Dept Biochem, Fac Med, Genet & Metab Dis Res & Invest Ctr, TR-34668 Istanbul, Turkey</subfield> <subfield code="a">Ece, Asli</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Marmara Univ, Dept Biochem, Fac Med, Genet & Metab Dis Res & Invest Ctr, TR-34668 Istanbul, Turkey</subfield> <subfield code="a">Ozaltin, Esra</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Uppsala Univ, Dept Chem, BMC & Sci Life Lab, SE-75124 Uppsala, Sweden</subfield> <subfield code="a">Ek, Bo</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Marmara Univ, Dept Biochem, Fac Med, Genet & Metab Dis Res & Invest Ctr, TR-34668 Istanbul, Turkey</subfield> <subfield code="a">Ozer, Nesrin Kartal</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Univ Jena, Dept Nutr Toxicol, Inst Nutr, D-07743 Jena, Germany</subfield> <subfield code="a">Grune, Tilman</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Uppsala Univ, Dept Chem, BMC & Sci Life Lab, SE-75124 Uppsala, Sweden</subfield> <subfield code="a">Bergquist, Jonas</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="u">Marmara Univ, Dept Biochem, Fac Med, Genet & Metab Dis Res & Invest Ctr, TR-34668 Istanbul, Turkey</subfield> <subfield code="a">Karademir, Betul</subfield> </datafield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="b">article</subfield> <subfield code="a">publication</subfield> </datafield> <datafield tag="542" ind1=" " ind2=" "> <subfield code="l">open</subfield> </datafield> <datafield tag="100" ind1=" " ind2=" "> <subfield code="u">Marmara Univ, Dept Biochem, Fac Med, Genet & Metab Dis Res & Invest Ctr, TR-34668 Istanbul, Turkey</subfield> <subfield code="a">Bozaykut, Perinur</subfield> </datafield> <datafield tag="260" ind1=" " ind2=" "> <subfield code="c">2013-01-01</subfield> </datafield> <controlfield tag="005">20210315093235.0</controlfield> <datafield tag="909" ind1="C" ind2="O"> <subfield code="o">oai:zenodo.org:15875</subfield> <subfield code="p">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="856" ind1="4" ind2=" "> <subfield code="z">md5:627275bae60e699a497dbb4e36141610</subfield> <subfield code="s">231</subfield> <subfield code="u">https://aperta.ulakbim.gov.trrecord/15875/files/bib-0c383390-2876-4d69-9021-3f3115d6dcd1.txt</subfield> </datafield> <datafield tag="540" ind1=" " ind2=" "> <subfield code="u">http://www.opendefinition.org/licenses/cc-by</subfield> <subfield code="a">Creative Commons Attribution</subfield> </datafield> <datafield tag="024" ind1=" " ind2=" "> <subfield code="a">10.1016/j.jprot.2013.06.025</subfield> <subfield code="2">doi</subfield> </datafield> </record>
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