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Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions

Hama, A. K.; Algso, M. A. S.; Kavak, E.; Kivrak, A.


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<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:creator>Hama, A. K.</dc:creator>
  <dc:creator>Algso, M. A. S.</dc:creator>
  <dc:creator>Kavak, E.</dc:creator>
  <dc:creator>Kivrak, A.</dc:creator>
  <dc:date>2020-01-01</dc:date>
  <dc:description>The Sonogashira cross coupling reaction of 2-bromo-5-(4-methoxyphenyl)thiophene and 1-ethynyl-2-(methylsulfanyl)benzene gave 2-(4-methoxyphenyl)-5-{[2-(methylsulfanyl)phenyl]ethynyl}thiophene which was subjected to electrophilic cyclization by the action of iodine to obtain 3-iodo-2-[5-(4-methoxyphenyl)thiophen-2-yl]-1-benzothiophene. Stille and Sonogashira coupling reactions of the latter afforded a series of new 3-substituted 2-[5-(4-methoxyphenyl)thiophen-2-yl]-1-benzothiophene derivatives of potential pharmacological interest.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/10523</dc:identifier>
  <dc:identifier>oai:zenodo.org:10523</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>RUSSIAN JOURNAL OF ORGANIC CHEMISTRY 56(7) 1272-1278</dc:source>
  <dc:title>Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
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