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Synthesis of Novel Benzothiophene Derivatives via Cyclization Reactions

Hama, A. K.; Algso, M. A. S.; Kavak, E.; Kivrak, A.


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        "affiliation": "Van Yuzuncu Yil Univ, Dept Chem, TR-65080 Van, Turkey", 
        "name": "Hama, A. K."
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      {
        "affiliation": "Van Yuzuncu Yil Univ, Dept Chem, TR-65080 Van, Turkey", 
        "name": "Algso, M. A. S."
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      {
        "affiliation": "Van Yuzuncu Yil Univ, Dept Chem, TR-65080 Van, Turkey", 
        "name": "Kavak, E."
      }, 
      {
        "affiliation": "Van Yuzuncu Yil Univ, Dept Chem, TR-65080 Van, Turkey", 
        "name": "Kivrak, A."
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    "description": "The Sonogashira cross coupling reaction of 2-bromo-5-(4-methoxyphenyl)thiophene and 1-ethynyl-2-(methylsulfanyl)benzene gave 2-(4-methoxyphenyl)-5-{[2-(methylsulfanyl)phenyl]ethynyl}thiophene which was subjected to electrophilic cyclization by the action of iodine to obtain 3-iodo-2-[5-(4-methoxyphenyl)thiophen-2-yl]-1-benzothiophene. Stille and Sonogashira coupling reactions of the latter afforded a series of new 3-substituted 2-[5-(4-methoxyphenyl)thiophen-2-yl]-1-benzothiophene derivatives of potential pharmacological interest.", 
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      "issue": "7", 
      "pages": "1272-1278", 
      "title": "RUSSIAN JOURNAL OF ORGANIC CHEMISTRY", 
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