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Intramolecular Heterocyclization of O-Propargylated Aromatic Hydroxyaldehydes as an Expedient Route to Substituted Chromenopyridines under Metal-Free Conditions

Keskin, Selbi; Balci, Metin


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  <dc:creator>Keskin, Selbi</dc:creator>
  <dc:creator>Balci, Metin</dc:creator>
  <dc:date>2015-01-01</dc:date>
  <dc:description>A concise and regioselective approach to the synthesis of chromenopyridine and chromenopyridinone derivatives was developed. The synthetic strategy relies on the O-propargylation of aromatic hydroxyaldehydes followed by reaction with propargylamine. The intramolecular cycloaddition reaction between the alkyne and azadiene, which is formed as an intermediate, furnished the desired skeletons.</dc:description>
  <dc:identifier>https://aperta.ulakbim.gov.trrecord/79515</dc:identifier>
  <dc:identifier>oai:zenodo.org:79515</dc:identifier>
  <dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
  <dc:rights>http://www.opendefinition.org/licenses/cc-by</dc:rights>
  <dc:source>ORGANIC LETTERS 17(4) 964-967</dc:source>
  <dc:title>Intramolecular Heterocyclization of O-Propargylated Aromatic Hydroxyaldehydes as an Expedient Route to Substituted Chromenopyridines under Metal-Free Conditions</dc:title>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:type>publication-article</dc:type>
</oai_dc:dc>
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