1 Ocak 2020 Dergi makalesi Açık Erişim

Taskin, Eylem; Guven, Celal; Kaya, Salih Tunc; Sariman, Melda; Emrence, Zeliha; Ekmekci, Sema Sirma; Abaci, Neslihan; Sevgiler, Yusuf; Akcakaya, Handan

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        "affiliation": "Nigde Omer Halisdemir Univ, Fac Med, Dept Physiol, Nigde, Turkey", 
        "name": "Taskin, Eylem"
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        "affiliation": "Nigde Omer Halisdemir Univ, Fac Med, Dept Biophys, Nigde, Turkey", 
        "name": "Guven, Celal"
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      {
        "affiliation": "Duzce Univ, Fac Arts & Sci, Dept Biol, Duzce, Turkey", 
        "name": "Kaya, Salih Tunc"
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      {
        "affiliation": "Istanbul Univ, Aziz Sancar Expt Med Res Inst, Dept Genet, Istanbul, Turkey", 
        "name": "Sariman, Melda"
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        "affiliation": "Istanbul Univ, Aziz Sancar Expt Med Res Inst, Dept Genet, Istanbul, Turkey", 
        "name": "Emrence, Zeliha"
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        "affiliation": "Istanbul Univ, Aziz Sancar Expt Med Res Inst, Dept Genet, Istanbul, Turkey", 
        "name": "Ekmekci, Sema Sirma"
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        "affiliation": "Istanbul Univ, Aziz Sancar Expt Med Res Inst, Dept Genet, Istanbul, Turkey", 
        "name": "Abaci, Neslihan"
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        "affiliation": "Adiyaman Univ, Fac Arts & Sci, Dept Biol, Adiyaman, Turkey", 
        "name": "Sevgiler, Yusuf"
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      {
        "affiliation": "Istanbul Univ, Fac Med, Dept Biophys, Istanbul, Turkey", 
        "name": "Akcakaya, Handan"
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    "description": "Purpose: Adriamycin (APR) is a commonly used anti-cancer drug. ADR has toxic effects on cardiomyocytes and leads to heart failure. However, the underlying mechanism(s) by which ADR causes heart failure is still not clarified exactly. The aim of present study is to investigate whether ADR-induced heart failure is mediated via HMGB1/TLR4 to initiate the apoptosis through MAPK/AMPK pathways.", 
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    "title": "Silencing HMGB1 expression inhibits adriamycin's heart toxicity via TLR4 dependent manner through MAPK signal transduction"
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