Dergi makalesi Açık Erişim
Taskin, Eylem; Guven, Celal; Kaya, Salih Tunc; Sariman, Melda; Emrence, Zeliha; Ekmekci, Sema Sirma; Abaci, Neslihan; Sevgiler, Yusuf; Akcakaya, Handan
Purpose: Adriamycin (APR) is a commonly used anti-cancer drug. ADR has toxic effects on cardiomyocytes and leads to heart failure. However, the underlying mechanism(s) by which ADR causes heart failure is still not clarified exactly. The aim of present study is to investigate whether ADR-induced heart failure is mediated via HMGB1/TLR4 to initiate the apoptosis through MAPK/AMPK pathways.
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bib-fafa85e0-f97f-4532-83ba-0be3294d700b.txt
md5:93959a568f6be3067c9a3cad8e896d64 |
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| Görüntülenme | 29 |
| İndirme | 5 |
| Veri hacmi | 1.4 kB |
| Tekil görüntülenme | 25 |
| Tekil indirme | 5 |