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Cucurbit[7]uril-Anchored Porphyrin-Based Multifunctional Molecular Platform for Photodynamic Antimicrobial and Cancer Therapy

Ozkan, Melis; Kumar, Yogesh; Keser, Yagmur; Hadi, Seyed E.; Tuncel, Donus


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{
  "@context": "https://schema.org/", 
  "@id": 72299, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Bilkent Univ, Natl Nanotechnol Res Ctr UNAM, Inst Mat Sci & Nanotechnol, TR-06800 Ankara, Turkey", 
      "name": "Ozkan, Melis"
    }, 
    {
      "@type": "Person", 
      "name": "Kumar, Yogesh"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Bilkent Univ, Natl Nanotechnol Res Ctr UNAM, Inst Mat Sci & Nanotechnol, TR-06800 Ankara, Turkey", 
      "name": "Keser, Yagmur"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Bilkent Univ, Natl Nanotechnol Res Ctr UNAM, Inst Mat Sci & Nanotechnol, TR-06800 Ankara, Turkey", 
      "name": "Hadi, Seyed E."
    }, 
    {
      "@type": "Person", 
      "name": "Tuncel, Donus"
    }
  ], 
  "datePublished": "2019-01-01", 
  "description": "Here we report a photoactive supramolecular assembly that is multifunctional and constructed by covalently linking four receptor molecules (cucurbit[7]uril) to a porphyrin derivative with suitable linkers. While this molecular platform serves very efficiently as a light-triggered broad-spectrum antibacterial agent, owing to its negligible dark cytotoxicity and the presence of host molecules (CB7), it can also be utilized as a vehicle to carry drug molecules for a combined chemo and photodynamic cancer therapy.", 
  "headline": "Cucurbit[7]uril-Anchored Porphyrin-Based Multifunctional Molecular Platform for Photodynamic Antimicrobial and Cancer Therapy", 
  "identifier": 72299, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "Cucurbit[7]uril-Anchored Porphyrin-Based Multifunctional Molecular Platform for Photodynamic Antimicrobial and Cancer Therapy", 
  "url": "https://aperta.ulakbim.gov.tr/record/72299"
}
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