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Akdal, Gulden; Kocoglu, Koray; Tanriverdizade, Tural; Bora, Elcin; Bademkiran, Fikret; Yuceyar, Ayse Nur; Ekmekci, Ozgul; Sengun, Ihsan Sukru; Karasoy, Hatice
<?xml version='1.0' encoding='utf-8'?> <resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd"> <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/7061</identifier> <creators> <creator> <creatorName>Akdal, Gulden</creatorName> <givenName>Gulden</givenName> <familyName>Akdal</familyName> </creator> <creator> <creatorName>Kocoglu, Koray</creatorName> <givenName>Koray</givenName> <familyName>Kocoglu</familyName> <affiliation>Dokuz Eylul Univ, Inst Hlth Sci, Dept Neurosci, Izmir, Turkey</affiliation> </creator> <creator> <creatorName>Tanriverdizade, Tural</creatorName> <givenName>Tural</givenName> <familyName>Tanriverdizade</familyName> <affiliation>Dokuz Eylul Univ, Inst Hlth Sci, Dept Neurosci, Izmir, Turkey</affiliation> </creator> <creator> <creatorName>Bora, Elcin</creatorName> <givenName>Elcin</givenName> <familyName>Bora</familyName> <affiliation>Dokuz Eylul Univ, Fac Med, Dept Med Genet, Izmir, Turkey</affiliation> </creator> <creator> <creatorName>Bademkiran, Fikret</creatorName> <givenName>Fikret</givenName> <familyName>Bademkiran</familyName> <affiliation>Ege Univ, Fac Med, Dept Neurol, Izmir, Turkey</affiliation> </creator> <creator> <creatorName>Yuceyar, Ayse Nur</creatorName> <givenName>Ayse Nur</givenName> <familyName>Yuceyar</familyName> <affiliation>Ege Univ, Fac Med, Dept Neurol, Izmir, Turkey</affiliation> </creator> <creator> <creatorName>Ekmekci, Ozgul</creatorName> <givenName>Ozgul</givenName> <familyName>Ekmekci</familyName> <affiliation>Ege Univ, Fac Med, Dept Neurol, Izmir, Turkey</affiliation> </creator> <creator> <creatorName>Sengun, Ihsan Sukru</creatorName> <givenName>Ihsan Sukru</givenName> <familyName>Sengun</familyName> <affiliation>Dokuz Eylul Univ, Fac Med, Dept Neurol, Izmir, Turkey</affiliation> </creator> <creator> <creatorName>Karasoy, Hatice</creatorName> <givenName>Hatice</givenName> <familyName>Karasoy</familyName> <affiliation>Ege Univ, Fac Med, Dept Neurol, Izmir, Turkey</affiliation> </creator> </creators> <titles> <title>Vestibular Impairment In Charcot-Marie-Tooth Disease</title> </titles> <publisher>Aperta</publisher> <publicationYear>2021</publicationYear> <dates> <date dateType="Issued">2021-01-01</date> </dates> <resourceType resourceTypeGeneral="Text">Journal article</resourceType> <alternateIdentifiers> <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/7061</alternateIdentifier> </alternateIdentifiers> <relatedIdentifiers> <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1007/s00415-020-10186-x</relatedIdentifier> </relatedIdentifiers> <rightsList> <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights> <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights> </rightsList> <descriptions> <description descriptionType="Abstract">Objective To find out if Charcot-Marie-Tooth (CMT) patients, who have peripheral vestibular as well as peripheral somatosensory impairment, have worse postural balance than those who do not. Methods We studied 32 patients with various CMT phenotypes and genotypes. Vestibular function was measured with the video head impulse test (vHIT) which tests vestibulo-ocular reflex (VOR) gain from each of the six semicircular canals in response to rapid head rotations. Postural balance was evaluated with a battery of four postural tests with emphasis on the modified clinical test of sensory integration in balance (mCTSIB). Results Half of the 32 patients had some impairment of vestibular function ranging from mild, affecting only 1-2 semicircular canals, to almost total affecting all 6 semicircular canals. Their mCTSIB scores correlated with VOR gain from the vertical rather than from the lateral semicircular canals. The worse the vertical VOR gain the worse the mCTSIB score. Conclusion We propose that any CMT patient could have clinically inapparent vestibular impairment that can be easily measured with the vHIT. This vestibular impairment could be contributing to their imbalance and could respond to a focused vestibular rehabilitation program.</description> </descriptions> </resource>
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