1 Ocak 2019 Dergi makalesi Açık Erişim

Karadeniz, Eda; Zora, Metin

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{
  "@context": "https://schema.org/", 
  "@id": 70551, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "affiliation": "Middle East Tech Univ, Dept Chem, TR-06800 Ankara, Turkey", 
      "name": "Karadeniz, Eda"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Middle East Tech Univ, Dept Chem, TR-06800 Ankara, Turkey", 
      "name": "Zora, Metin"
    }
  ], 
  "datePublished": "2019-01-01", 
  "description": "A simple and general one-pot method for the synthesis of spiro-2 H -pyrroles has been developed. Initially, cyclohexane-embedded -enaminones with internal alkyne functionality were synthesized by conjugate addition of 1-ethynylcyclohexylamine to ,-alkynic ketones, followed by palladium-catalyzed coupling of the resulting N -propargylic -enaminones with aryl iodides. When subjected to basic conditions, the cyclohexane-embedded -enaminones with internal alkyne functionality underwent tandem nucleophilic cyclization and benzylic C-H oxidation to furnish 3,4-diaryloyl-1-azaspiro[4.5]deca-1,3-diene derivatives in good yields.", 
  "headline": "One-Pot Synthesis of Spiro-2H-pyrroles fromN-Propargylic beta-Enaminones", 
  "identifier": 70551, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "One-Pot Synthesis of Spiro-2H-pyrroles fromN-Propargylic beta-Enaminones", 
  "url": "https://aperta.ulakbim.gov.tr/record/70551"
}