Dergi makalesi Açık Erişim
Karadeniz, Eda; Zora, Metin
{ "DOI": "10.1055/s-0037-1611816", "abstract": "A simple and general one-pot method for the synthesis of spiro-2 H -pyrroles has been developed. Initially, cyclohexane-embedded -enaminones with internal alkyne functionality were synthesized by conjugate addition of 1-ethynylcyclohexylamine to ,-alkynic ketones, followed by palladium-catalyzed coupling of the resulting N -propargylic -enaminones with aryl iodides. When subjected to basic conditions, the cyclohexane-embedded -enaminones with internal alkyne functionality underwent tandem nucleophilic cyclization and benzylic C-H oxidation to furnish 3,4-diaryloyl-1-azaspiro[4.5]deca-1,3-diene derivatives in good yields.", "author": [ { "family": "Karadeniz", "given": " Eda" }, { "family": "Zora", "given": " Metin" } ], "container_title": "SYNLETT", "id": "70551", "issue": "10", "issued": { "date-parts": [ [ 2019, 1, 1 ] ] }, "page": "1231-1236", "title": "One-Pot Synthesis of Spiro-2H-pyrroles fromN-Propargylic beta-Enaminones", "type": "article-journal", "volume": "30" }
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