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High pKa variability of cysteine residues in structural databases and the effect of H-bond contributions

Marino, Stefano M.; Soylu, Inanc


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/65875</identifier>
  <creators>
    <creator>
      <creatorName>Marino, Stefano M.</creatorName>
      <givenName>Stefano M.</givenName>
      <familyName>Marino</familyName>
      <affiliation>Akdeniz Univ, Dept Agr Biotechnol, TR-07058 Antalya, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Soylu, Inanc</creatorName>
      <givenName>Inanc</givenName>
      <familyName>Soylu</familyName>
      <affiliation>Akdeniz Univ, Dept Agr Biotechnol, TR-07058 Antalya, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>High Pka Variability Of Cysteine Residues In Structural Databases And The Effect Of H-Bond Contributions</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2014</publicationYear>
  <dates>
    <date dateType="Issued">2014-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/65875</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.5505/tjb.2014.55823</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Objective: Our first objective was to extensively compare two most common empirical protein pKa predictors, propka1.0 (ppka1) and propka3.0 (ppka3); we have specifically compared them as tools for high-throughput analyses of structural datasets with a particular focus on the amino acid Cysteine (Cys); afterwards, our goal was to assess their performances with known instances of reactive Cys residues.</description>
  </descriptions>
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