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High pKa variability of cysteine residues in structural databases and the effect of H-bond contributions

Marino, Stefano M.; Soylu, Inanc


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{
  "DOI": "10.5505/tjb.2014.55823", 
  "abstract": "Objective: Our first objective was to extensively compare two most common empirical protein pKa predictors, propka1.0 (ppka1) and propka3.0 (ppka3); we have specifically compared them as tools for high-throughput analyses of structural datasets with a particular focus on the amino acid Cysteine (Cys); afterwards, our goal was to assess their performances with known instances of reactive Cys residues.", 
  "author": [
    {
      "family": "Marino", 
      "given": " Stefano M."
    }, 
    {
      "family": "Soylu", 
      "given": " Inanc"
    }
  ], 
  "container_title": "TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI", 
  "id": "65875", 
  "issue": "4", 
  "issued": {
    "date-parts": [
      [
        2014, 
        1, 
        1
      ]
    ]
  }, 
  "page": "435-+", 
  "title": "High pKa variability of cysteine residues in structural databases and the effect of H-bond contributions", 
  "type": "article-journal", 
  "volume": "39"
}
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