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Data on pharmacological applications and hypothermia protection against in vitro oxygen-glucose-deprivation-related neurodegeneration of adult rat CA1 region

Oz, Pinar; Saybasili, Hale


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/45101</identifier>
  <creators>
    <creator>
      <creatorName>Oz, Pinar</creatorName>
      <givenName>Pinar</givenName>
      <familyName>Oz</familyName>
    </creator>
    <creator>
      <creatorName>Saybasili, Hale</creatorName>
      <givenName>Hale</givenName>
      <familyName>Saybasili</familyName>
      <affiliation>Bogazici Univ Kandilli Campus, Inst Biomed Engn, TR-34684 Istanbul, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Data On Pharmacological Applications And Hypothermia Protection Against In Vitro Oxygen-Glucose-Deprivation-Related Neurodegeneration Of Adult Rat Ca1 Region</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2017</publicationYear>
  <dates>
    <date dateType="Issued">2017-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/45101</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1016/j.dib.2016.12.009</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">In this data article, the level of chemical neuroprotection against oxygen-glucose-deprivation (OGD)-related neurodegeneration in CAl was analyzed using the measurements on CAl stratum pyramidale (CA1 sp) width. Adult rat hippocampal slices were incubated in OGD medium for 60 min to create a model for severe ischemic conditions. Alternatively, control slices were incubated in artificial cerebrospinal fluid (ACSF) for 60 min. A study of OGD induced neurodegeneration and partial prevention by pharmacological agents reported; baclofen, memantine and 1.-carnitine effects were included. Also, the use of hypothermia was reported (P. Oz, H. Saybasili, 2016) [1].</description>
  </descriptions>
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