1 Ocak 2008 Dergi makalesi Açık Erişim

Gur-Dedeoglu, Bala; Konu, Ozlen; Kir, Serkan; Ozturk, Ahmet Rasit; Bozkurt, Betul; Ergul, Gulusan; Yulug, Isik G.

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/41529</identifier>
  <creators>
    <creator>
      <creatorName>Gur-Dedeoglu, Bala</creatorName>
      <givenName>Bala</givenName>
      <familyName>Gur-Dedeoglu</familyName>
      <affiliation>Bilkent Univ, Fac Sci, Dept Mol Biol &amp; Genet, TR-06800 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Konu, Ozlen</creatorName>
      <givenName>Ozlen</givenName>
      <familyName>Konu</familyName>
      <affiliation>Bilkent Univ, Fac Sci, Dept Mol Biol &amp; Genet, TR-06800 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kir, Serkan</creatorName>
      <givenName>Serkan</givenName>
      <familyName>Kir</familyName>
      <affiliation>Bilkent Univ, Fac Sci, Dept Mol Biol &amp; Genet, TR-06800 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozturk, Ahmet Rasit</creatorName>
      <givenName>Ahmet Rasit</givenName>
      <familyName>Ozturk</familyName>
      <affiliation>Bilkent Univ, Fac Sci, Dept Mol Biol &amp; Genet, TR-06800 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Bozkurt, Betul</creatorName>
      <givenName>Betul</givenName>
      <familyName>Bozkurt</familyName>
      <affiliation>Ankara Numune Res &amp; Teaching Hosp, Dept Gen Surg, TR-06100 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ergul, Gulusan</creatorName>
      <givenName>Gulusan</givenName>
      <familyName>Ergul</familyName>
      <affiliation>Ankara Numune Res &amp; Teaching Hosp, Dept Pathol, TR-06100 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yulug, Isik G.</creatorName>
      <givenName>Isik G.</givenName>
      <familyName>Yulug</familyName>
      <affiliation>Bilkent Univ, Fac Sci, Dept Mol Biol &amp; Genet, TR-06800 Ankara, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>A Resampling-Based Meta-Analysis For Detection Of Differential Gene Expression In Breast Cancer</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2008</publicationYear>
  <dates>
    <date dateType="Issued">2008-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/41529</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1186/1471-2407-8-396</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Background: Accuracy in the diagnosis of breast cancer and classification of cancer subtypes has improved over the years with the development of well-established immunohistopathological criteria. More recently, diagnostic gene-sets at the mRNA expression level have been tested as better predictors of disease state. However, breast cancer is heterogeneous in nature; thus extraction of differentially expressed gene-sets that stably distinguish normal tissue from various pathologies poses challenges. Meta-analysis of high-throughput expression data using a collection of statistical methodologies leads to the identification of robust tumor gene expression signatures.</description>
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