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Gur-Dedeoglu, Bala; Konu, Ozlen; Kir, Serkan; Ozturk, Ahmet Rasit; Bozkurt, Betul; Ergul, Gulusan; Yulug, Isik G.
{ "DOI": "10.1186/1471-2407-8-396", "abstract": "Background: Accuracy in the diagnosis of breast cancer and classification of cancer subtypes has improved over the years with the development of well-established immunohistopathological criteria. More recently, diagnostic gene-sets at the mRNA expression level have been tested as better predictors of disease state. However, breast cancer is heterogeneous in nature; thus extraction of differentially expressed gene-sets that stably distinguish normal tissue from various pathologies poses challenges. Meta-analysis of high-throughput expression data using a collection of statistical methodologies leads to the identification of robust tumor gene expression signatures.", "author": [ { "family": "Gur-Dedeoglu", "given": " Bala" }, { "family": "Konu", "given": " Ozlen" }, { "family": "Kir", "given": " Serkan" }, { "family": "Ozturk", "given": " Ahmet Rasit" }, { "family": "Bozkurt", "given": " Betul" }, { "family": "Ergul", "given": " Gulusan" }, { "family": "Yulug", "given": " Isik G." } ], "container_title": "BMC CANCER", "id": "41529", "issued": { "date-parts": [ [ 2008, 1, 1 ] ] }, "title": "A resampling-based meta-analysis for detection of differential gene expression in breast cancer", "type": "article-journal", "volume": "8" }
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