Dergi makalesi Açık Erişim
Gur-Dedeoglu, Bala; Konu, Ozlen; Kir, Serkan; Ozturk, Ahmet Rasit; Bozkurt, Betul; Ergul, Gulusan; Yulug, Isik G.
{
"DOI": "10.1186/1471-2407-8-396",
"abstract": "Background: Accuracy in the diagnosis of breast cancer and classification of cancer subtypes has improved over the years with the development of well-established immunohistopathological criteria. More recently, diagnostic gene-sets at the mRNA expression level have been tested as better predictors of disease state. However, breast cancer is heterogeneous in nature; thus extraction of differentially expressed gene-sets that stably distinguish normal tissue from various pathologies poses challenges. Meta-analysis of high-throughput expression data using a collection of statistical methodologies leads to the identification of robust tumor gene expression signatures.",
"author": [
{
"family": "Gur-Dedeoglu",
"given": " Bala"
},
{
"family": "Konu",
"given": " Ozlen"
},
{
"family": "Kir",
"given": " Serkan"
},
{
"family": "Ozturk",
"given": " Ahmet Rasit"
},
{
"family": "Bozkurt",
"given": " Betul"
},
{
"family": "Ergul",
"given": " Gulusan"
},
{
"family": "Yulug",
"given": " Isik G."
}
],
"container_title": "BMC CANCER",
"id": "41529",
"issued": {
"date-parts": [
[
2008,
1,
1
]
]
},
"title": "A resampling-based meta-analysis for detection of differential gene expression in breast cancer",
"type": "article-journal",
"volume": "8"
}
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