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Antioxidant and Anticholinesterase Assets and Liquid Chromatography-Mass Spectrometry Preface of Various Fresh-Water and Marine Macroalgae

Murat, Kartal; Ilkay, Orhan; Mahmud, Abu-Asaker; Senol, F. S.; Tahir, Atici; Bilge, Sener


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    "creators": [
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        "affiliation": "Ankara Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey", 
        "name": "Murat, Kartal"
      }, 
      {
        "affiliation": "Gazi Univ, Dept Pharmacognosy, Fac Pharm, TR-06330 Ankara, Turkey", 
        "name": "Ilkay, Orhan"
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      {
        "affiliation": "Ankara Univ, Fac Pharm, Dept Pharmacognosy, TR-06100 Ankara, Turkey", 
        "name": "Mahmud, Abu-Asaker"
      }, 
      {
        "affiliation": "Gazi Univ, Dept Pharmacognosy, Fac Pharm, TR-06330 Ankara, Turkey", 
        "name": "Senol, F. S."
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      {
        "affiliation": "Gazi Univ, Fac Educ, Dept Biol, TR-06330 Ankara, Turkey", 
        "name": "Tahir, Atici"
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      {
        "name": "Bilge, Sener"
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    "description": "The ethanol extracts from the fresh-water algae; Chara hispida L., Cladophora glomerata (Dilw.) Kutz, C. fracta (Dilw.) Kutz, Spirogyra gratiana Transeau, Mougeotia sp. (C.A. Agardh), Vaucheria sessilis (Vauch.) De Candolle, Geminella mutabilis (Breb.) Wille, the fresh-water plants; Ranunculus rionii Lagger and Ceratophyllum demersum L., as well as the marine algae; Sciniaia furcellata (Turn.) J. Agardh, Dictyota dichotoma (Huds.) Lam., Padina vickersiae Hoyt, Halopteris scoparia (L.) Sauvagau, and the sea grass; Posidonia oceanica (L.) Dell. were assessed in vitro for their antioxidant and anti-acetylcholinesterase (AChE) activities. Antioxidant activity was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity test at 0.125, 0.25, 0.5, 1.0, and 2.0 mg ml(-1) and ferric-reducing antioxidant power assay (FRAP) at 0.5, 1.0, and 2.0 mg ml(-1) concentrations. Total phenolic contents of the extracts were determined using Folin-Ciocalteau's reagent. The extracts were further analyzed qualitatively by LC-DAD-MS. S. gratiana had the best antioxidant activity, followed by R. rionii. LC-DAD-MS showed rich gallic acid and its ethyl ester contents in S. gratiana, while prosperous vitamin C content has been detected in P. oceanica for the first time in this study. S. gratiana possessed the highest inhibition (42.5 +/- 2.28%) at 2.0 mg ml-1 against AChE.", 
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      "issue": "20", 
      "pages": "291-297", 
      "title": "PHARMACOGNOSY MAGAZINE", 
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    "publication_date": "2009-01-01", 
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