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Synthesis of beta-chloro-alpha-aminophosphonate derivatives via the regioselective ring opening of unactivated aziridine-2-phosphonates

Polat-Cakir, Sidika; Beksultanova, Nurzhan; Dogan, Ozdemir


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{
  "DOI": "10.1080/10426507.2018.1513521", 
  "abstract": "A series of unactivated racemic and chiral aziridine-2-phosphonates were synthesized by modified Gabriel-Cromwell reaction. Ring opening reaction of the synthesized phosphonates by gaseous HCl provided access to a wide range of biologically interesting novel beta-chloro-alpha-aminophosphonates. All reactions toward each of the above-mentioned products can be conducted regioselectively in high yields.", 
  "author": [
    {
      "family": "Polat-Cakir", 
      "given": " Sidika"
    }, 
    {
      "family": "Beksultanova", 
      "given": " Nurzhan"
    }, 
    {
      "family": "Dogan", 
      "given": " Ozdemir"
    }
  ], 
  "container_title": "PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS", 
  "id": "33007", 
  "issue": "12", 
  "issued": {
    "date-parts": [
      [
        2018, 
        1, 
        1
      ]
    ]
  }, 
  "page": "858-864", 
  "title": "Synthesis of beta-chloro-alpha-aminophosphonate derivatives via the regioselective ring opening of unactivated aziridine-2-phosphonates", 
  "type": "article-journal", 
  "volume": "193"
}
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