1 Ocak 2023 Dergi makalesi Açık Erişim

Durdu, Salih; Cihan, Gizem; Yalcin, Emine; Cavusoglu, Kultigin; Altinkok, Atilgan; Sagcan, Hasan; Yurtsever, Ilknur; Usta, Metin

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    <subfield code="a">Surface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO&lt;sub&gt;2&lt;/sub&gt; nanotube surfaces</subfield>
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    <subfield code="a">&lt;p&gt;In this work, to improve antibacterial, biocompatible and bioactive properties of commercial pure titanium (cp-Ti) for implant applications, the Zn-deposited nanotube surfaces were fabricated on cp-Ti by using combined anodic oxidation (AO) and physical vapor deposition (PVD-TE) methods. Homogenous elemental distributions were observed through all surfaces. Moreover, Zn-deposited surfaces exhibited hydrophobic character while bare Ti surfaces were hydrophilic. Due to the biodegradable behavior of Zn on the nanotube surface, Zn-deposited nanotube surfaces showed higher corrosion current density than bare cp-Ti surface in SBF conditions as expected. In vitro biological properties such as cell viability, ALP activity, protein adsorption, hemolytic activity and antibacterial activity for Gram-positive and Gram-negative bacteria of all surfaces were investigated in detail. Cell viability, ALP activity and antibacterial properties of Zn-deposited nanotube surfaces were significantly improved with respect to bare cp-Ti. Moreover, hemolytic activity and protein adsorption of Zn-deposited nanotube surfaces were decreased. According to these results; a bioactive, biocompatible and antibacterial Zn-deposited nanotube surfaces produced on cp-Ti by using combined AO and PVD techniques can have potential for orthopedic and dental implant applications.&lt;/p&gt;</subfield>
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