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Surface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO<sub>2</sub> nanotube surfaces

Durdu, Salih; Cihan, Gizem; Yalcin, Emine; Cavusoglu, Kultigin; Altinkok, Atilgan; Sagcan, Hasan; Yurtsever, Ilknur; Usta, Metin


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{
  "DOI": "10.1038/s41598-023-38733-2", 
  "abstract": "<p>In this work, to improve antibacterial, biocompatible and bioactive properties of commercial pure titanium (cp-Ti) for implant applications, the Zn-deposited nanotube surfaces were fabricated on cp-Ti by using combined anodic oxidation (AO) and physical vapor deposition (PVD-TE) methods. Homogenous elemental distributions were observed through all surfaces. Moreover, Zn-deposited surfaces exhibited hydrophobic character while bare Ti surfaces were hydrophilic. Due to the biodegradable behavior of Zn on the nanotube surface, Zn-deposited nanotube surfaces showed higher corrosion current density than bare cp-Ti surface in SBF conditions as expected. In vitro biological properties such as cell viability, ALP activity, protein adsorption, hemolytic activity and antibacterial activity for Gram-positive and Gram-negative bacteria of all surfaces were investigated in detail. Cell viability, ALP activity and antibacterial properties of Zn-deposited nanotube surfaces were significantly improved with respect to bare cp-Ti. Moreover, hemolytic activity and protein adsorption of Zn-deposited nanotube surfaces were decreased. According to these results; a bioactive, biocompatible and antibacterial Zn-deposited nanotube surfaces produced on cp-Ti by using combined AO and PVD techniques can have potential for orthopedic and dental implant applications.</p>", 
  "author": [
    {
      "family": "Durdu", 
      "given": " Salih"
    }, 
    {
      "family": "Cihan", 
      "given": " Gizem"
    }, 
    {
      "family": "Yalcin", 
      "given": " Emine"
    }, 
    {
      "family": "Cavusoglu", 
      "given": " Kultigin"
    }, 
    {
      "family": "Altinkok", 
      "given": " Atilgan"
    }, 
    {
      "family": "Sagcan", 
      "given": " Hasan"
    }, 
    {
      "family": "Yurtsever", 
      "given": " Ilknur"
    }, 
    {
      "family": "Usta", 
      "given": " Metin"
    }
  ], 
  "container_title": "SCIENTIFIC REPORTS", 
  "id": "271842", 
  "issue": "1", 
  "issued": {
    "date-parts": [
      [
        2023, 
        1, 
        1
      ]
    ]
  }, 
  "page": "15", 
  "title": "Surface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO<sub>2</sub> nanotube surfaces", 
  "type": "article-journal", 
  "volume": "13"
}
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