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CD4+and CD25+T-cell response to short-time interferon-beta therapy on IL10, IL23A and FOXP3 genes in multiple sclerosis patients

Gezmis, Hazal; Doran, Tansu; Mayda Domac, Fusun; Yucel, Deniz; Karaci, Rahsan; Kirac, Deniz


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{
  "@context": "https://schema.org/", 
  "@id": 238370, 
  "@type": "ScholarlyArticle", 
  "creator": [
    {
      "@type": "Person", 
      "name": "Gezmis, Hazal"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Yeditepe Univ, Dept Med Biol, Fac Med, TR-34755 Istanbul, Turkey", 
      "name": "Doran, Tansu"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Hlth Sci, Erenkoy Mental & Nervous Dis Training & Res Hosp, Dept Neurol, Istanbul, Turkey", 
      "name": "Mayda Domac, Fusun"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Acibadem Mehmet Ali Aydinlar Univ, Dept Histol & Embryol, Fac Med, Istanbul, Turkey", 
      "name": "Yucel, Deniz"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Univ Hlth Sci, Erenkoy Mental & Nervous Dis Training & Res Hosp, Dept Neurol, Istanbul, Turkey", 
      "name": "Karaci, Rahsan"
    }, 
    {
      "@type": "Person", 
      "affiliation": "Yeditepe Univ, Dept Med Biol, Fac Med, TR-34755 Istanbul, Turkey", 
      "name": "Kirac, Deniz"
    }
  ], 
  "datePublished": "2021-01-01", 
  "description": "Aim of the Study Interferon-beta (IFN-beta), multiple sclerosis (MS) drug for years, does not have therapeutic effects on each patient. Yet, a considerable portion has experienced no therapeutic response to IFN-beta. Therefore, it is necessary to determine disease-specific biomarkers that affect drug response. Here, we aimed to determine the effects of interleukin 10 (IL10) and 23 (IL23A), as well as forkhead box P3 (FOXP3) genes on MS after IFN-beta therapy.", 
  "headline": "CD4+and CD25+T-cell response to short-time interferon-beta therapy on IL10, IL23A and FOXP3 genes in multiple sclerosis patients", 
  "identifier": 238370, 
  "image": "https://aperta.ulakbim.gov.tr/static/img/logo/aperta_logo_with_icon.svg", 
  "license": "http://www.opendefinition.org/licenses/cc-by", 
  "name": "CD4+and CD25+T-cell response to short-time interferon-beta therapy on IL10, IL23A and FOXP3 genes in multiple sclerosis patients", 
  "url": "https://aperta.ulakbim.gov.tr/record/238370"
}
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