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CD4+and CD25+T-cell response to short-time interferon-beta therapy on IL10, IL23A and FOXP3 genes in multiple sclerosis patients

Gezmis, Hazal; Doran, Tansu; Mayda Domac, Fusun; Yucel, Deniz; Karaci, Rahsan; Kirac, Deniz


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/238370</identifier>
  <creators>
    <creator>
      <creatorName>Gezmis, Hazal</creatorName>
      <givenName>Hazal</givenName>
      <familyName>Gezmis</familyName>
    </creator>
    <creator>
      <creatorName>Doran, Tansu</creatorName>
      <givenName>Tansu</givenName>
      <familyName>Doran</familyName>
      <affiliation>Yeditepe Univ, Dept Med Biol, Fac Med, TR-34755 Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Mayda Domac, Fusun</creatorName>
      <givenName>Fusun</givenName>
      <familyName>Mayda Domac</familyName>
      <affiliation>Univ Hlth Sci, Erenkoy Mental &amp; Nervous Dis Training &amp; Res Hosp, Dept Neurol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yucel, Deniz</creatorName>
      <givenName>Deniz</givenName>
      <familyName>Yucel</familyName>
      <affiliation>Acibadem Mehmet Ali Aydinlar Univ, Dept Histol &amp; Embryol, Fac Med, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karaci, Rahsan</creatorName>
      <givenName>Rahsan</givenName>
      <familyName>Karaci</familyName>
      <affiliation>Univ Hlth Sci, Erenkoy Mental &amp; Nervous Dis Training &amp; Res Hosp, Dept Neurol, Istanbul, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kirac, Deniz</creatorName>
      <givenName>Deniz</givenName>
      <familyName>Kirac</familyName>
      <affiliation>Yeditepe Univ, Dept Med Biol, Fac Med, TR-34755 Istanbul, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Cd4+And Cd25+T-Cell Response To Short-Time Interferon-Beta Therapy On Il10, Il23A And Foxp3 Genes In Multiple Sclerosis Patients</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2021</publicationYear>
  <dates>
    <date dateType="Issued">2021-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/238370</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1111/ijcp.14238</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Aim of the Study Interferon-beta (IFN-beta), multiple sclerosis (MS) drug for years, does not have therapeutic effects on each patient. Yet, a considerable portion has experienced no therapeutic response to IFN-beta. Therefore, it is necessary to determine disease-specific biomarkers that affect drug response. Here, we aimed to determine the effects of interleukin 10 (IL10) and 23 (IL23A), as well as forkhead box P3 (FOXP3) genes on MS after IFN-beta therapy.</description>
  </descriptions>
</resource>
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