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ALX-Related Frontonasal Dysplasias: Clinical Characteristics and Surgical Management

Vargel, Ibrahim; Canter, Halil Ibrahim; Kucukguven, Arda; Aydin, Asim; Ozgur, Figen


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        "affiliation": "Hacettepe Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-06080 Ankara, Turkey", 
        "name": "Vargel, Ibrahim"
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      {
        "affiliation": "Anadolu Med Ctr, Dept Plast & Reconstruct Surg, Istanbul, Turkey", 
        "name": "Canter, Halil Ibrahim"
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      {
        "affiliation": "Hacettepe Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-06080 Ankara, Turkey", 
        "name": "Kucukguven, Arda"
      }, 
      {
        "affiliation": "Suleyman Demirel Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, Isparta, Turkey", 
        "name": "Aydin, Asim"
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      {
        "affiliation": "Hacettepe Univ, Fac Med, Dept Plast Reconstruct & Aesthet Surg, TR-06080 Ankara, Turkey", 
        "name": "Ozgur, Figen"
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    "description": "Aim: The term frontonasal dysplasia (FND) represents a spectrum of anomalies and its genetics have not been well defined. Recently, the critical role of the aristaless-like homeobox (ALX) gene family on the craniofacial development has been discovered. In the present study, we aimed to propose a systematic surgical treatment plan for the ALX-related FNDs according to the genotypic classification as well as demonstrating their clinical characteristics to help surgeons diagnose the underlying pathology accurately.", 
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      "issue": "5", 
      "pages": "637-643", 
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