Dergi makalesi Açık Erişim

ALX-Related Frontonasal Dysplasias: Clinical Characteristics and Surgical Management

2022    Vargel, Ibrahim; Canter, Halil Ibrahim; Kucukguven, Arda; Aydin, Asim; Ozgur, Figen

Aim: The term frontonasal dysplasia (FND) represents a spectrum of anomalies and its genetics have not been well defined. Recently, the critical role of the aristaless-like homeobox (ALX) gene family on the craniofacial development has been discovered. In the present study, we aimed to propose a systematic surgical treatment plan for the ALX-related FNDs according to the genotypic classification as well as demonstrating their clinical characteristics to help surgeons diagnose the underlying pathology accurately.