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Proteomic Analysis of a hom-Disrupted, Cephamycin C Overproducing Streptomyces clavuligerus

Unsaldi, Eser; Kurt-Kizildogan, Aslihan; Ozcan, Servet; Becher, Dorte; Voigt, Birgit; Aktas, Caner; Ozcengiz, Gulay


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    <subfield code="a">Background: Streptomyces clavuligerus is prolific producer of cephamycin C, a medically important antibiotic. In our former study, cephamycin C titer was 2-fold improved by disrupting homoserine dehydrogenase (hom) gene of aspartate pahway in Streptomyces clavuligerus NR-RL 3585.</subfield>
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