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Proteomic Analysis of a hom-Disrupted, Cephamycin C Overproducing Streptomyces clavuligerus

Unsaldi, Eser; Kurt-Kizildogan, Aslihan; Ozcan, Servet; Becher, Dorte; Voigt, Birgit; Aktas, Caner; Ozcengiz, Gulay


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        "name": "Unsaldi, Eser"
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        "affiliation": "Ondokuz Mayis Univ, Dept Agr Biotechnol, TR-55139 Samsun, Turkey", 
        "name": "Kurt-Kizildogan, Aslihan"
      }, 
      {
        "affiliation": "Erciyes Univ, Dept Biol, TR-38280 Kayseri, Turkey", 
        "name": "Ozcan, Servet"
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      {
        "affiliation": "Ernst Moritz Arndt Univ Greifswald, Inst Microbiol, D-17487 Greifswald, Germany", 
        "name": "Becher, Dorte"
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        "affiliation": "Ernst Moritz Arndt Univ Greifswald, Inst Microbiol, D-17487 Greifswald, Germany", 
        "name": "Voigt, Birgit"
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        "affiliation": "Middle East Tech Univ, Dept Biol Sci, TR-06800 Ankara, Turkey", 
        "name": "Aktas, Caner"
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        "affiliation": "Middle East Tech Univ, Dept Biol Sci, TR-06800 Ankara, Turkey", 
        "name": "Ozcengiz, Gulay"
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    "description": "Background: Streptomyces clavuligerus is prolific producer of cephamycin C, a medically important antibiotic. In our former study, cephamycin C titer was 2-fold improved by disrupting homoserine dehydrogenase (hom) gene of aspartate pahway in Streptomyces clavuligerus NR-RL 3585.", 
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