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Vitamin D receptor gene polymorphisms and male breast cancer risk in Turkish population

Kizildag, S.; Gulsu, E.; Bagci, O.; Yuksel, E.; Canda, T.


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    <subfield code="a">Purpose: Male breast cancer (MBC) is a rare disease. However; as global populace ages, there is a trend for MBC increase. Although its etiology is still unclear, constitutional, environmental, hormonal (abnormalities in estrogen/androgen balance) and genetic (positive family history, Klinefelter syndrome, mutations in BRCA1 and BRCA2) risk factors are already known. One potential target is the vitamin D receptor (VDR). We have investigated whether polymorphisms in the VDR gene are associated with altered MBC risk in a Turkish population.</subfield>
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