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A microfluidic based differential plasmon resonance sensor

Okan, Melih; Balci, Osman; Kocabas, Coskun


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{
  "DOI": "10.1016/j.snb.2011.08.046", 
  "abstract": "A new type of differential surface plasmon (SPR) sensor integrated with a microfluidic system is presented. The working principle of the microfluidic device is based on hydrodynamic modulation of two laminar streams inside a microchannel to provide periodic changes of the environment on the SPR sensor. The modulated reflectance is then demodulated using a lock-in amplifier. The presented sensor provides sensitivities of index of refraction about 4 x 10(-8) RIU together with a 4 orders of magnitude dynamic range. This method demonstrates a sensitive detection scheme which could be used for label-free detection. (C) 2011 Elsevier B.V. All rights reserved.", 
  "author": [
    {
      "family": "Okan", 
      "given": " Melih"
    }, 
    {
      "family": "Balci", 
      "given": " Osman"
    }, 
    {
      "family": "Kocabas", 
      "given": " Coskun"
    }
  ], 
  "container_title": "SENSORS AND ACTUATORS B-CHEMICAL", 
  "id": "20821", 
  "issue": "1", 
  "issued": {
    "date-parts": [
      [
        2011, 
        1, 
        1
      ]
    ]
  }, 
  "page": "670-676", 
  "title": "A microfluidic based differential plasmon resonance sensor", 
  "type": "article-journal", 
  "volume": "160"
}
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