1 Ocak 2013 Dergi makalesi Açık Erişim

Kayhan, Gulay Erdogan; Gul, Mehmet; Kayhan, Basak; Gedik, Ender; Ozgul, Ulku; Kurtoglu, Elcin Latife; Durmus, Mahmut; Ersoy, Mehmet Ozcan

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        "affiliation": "Inonu Univ, Turgut Ozal Med Ctr, Fac Med, Dept Anesthesiol & Reanimat, TR-44100 Malatya, Turkey", 
        "name": "Kayhan, Gulay Erdogan"
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      {
        "affiliation": "Inonu Univ, Turgut Ozal Med Ctr, Fac Med, Dept Histol & Embryol, TR-44100 Malatya, Turkey", 
        "name": "Gul, Mehmet"
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      {
        "affiliation": "Inonu Univ, Turgut Ozal Med Ctr, Fac Med, Dept Med Biol & Genet, TR-44100 Malatya, Turkey", 
        "name": "Kayhan, Basak"
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      {
        "affiliation": "Inonu Univ, Turgut Ozal Med Ctr, Fac Med, Dept Anesthesiol & Reanimat, TR-44100 Malatya, Turkey", 
        "name": "Gedik, Ender"
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      {
        "affiliation": "Inonu Univ, Turgut Ozal Med Ctr, Fac Med, Dept Anesthesiol & Reanimat, TR-44100 Malatya, Turkey", 
        "name": "Ozgul, Ulku"
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      {
        "affiliation": "Inonu Univ, Turgut Ozal Med Ctr, Fac Med, Dept Med Biol & Genet, TR-44100 Malatya, Turkey", 
        "name": "Kurtoglu, Elcin Latife"
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      {
        "affiliation": "Inonu Univ, Turgut Ozal Med Ctr, Fac Med, Dept Anesthesiol & Reanimat, TR-44100 Malatya, Turkey", 
        "name": "Durmus, Mahmut"
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      {
        "affiliation": "Inonu Univ, Turgut Ozal Med Ctr, Fac Med, Dept Anesthesiol & Reanimat, TR-44100 Malatya, Turkey", 
        "name": "Ersoy, Mehmet Ozcan"
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    "description": "Background: Since sedatives are often administered to immune-compromised and critically ill patients, our understanding of immunomodulation by sedation will be critical. Dexmedetomidine, a selective alpha(2)-adrenergic receptor agonist, is often used for sedation and analgesia especially in intensive care units. There are conflicting and little data concerning both the effect and the mechanism of dexmedetomidine on immune response. In our study, we aimed to investigate the effect of dexmedetomidine on immune system at two different doses (5 mu g.kg(-1) and 30 mu g.kg(-1)) during inflammatory bowel disease by using an experimental model, which resembles both systemic and local inflammation.", 
    "doi": "10.1016/j.jss.2013.03.028", 
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    "journal": {
      "issue": "2", 
      "pages": "733-741", 
      "title": "JOURNAL OF SURGICAL RESEARCH", 
      "volume": "183"
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      "title": "Dergi makalesi", 
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    "title": "Dexmedetomidine ameliorates TNBS-induced colitis by inducing immunomodulator effect"
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