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Proteomics Analysis of CA1 Region of the Hippocampus in Pre-, Progression and Pathological Stages in a Mouse Model of the Alzheimer's Disease

Gurel, Busra; Cansev, Mehmet; Koc, Cansu; Ocalan, Busra; Cakir, Aysen; Aydin, Sami; Kahveci, Nevzat; Ulus, Ismail Hakki; Sahin, Betul; Basar, Merve Karayel; Baykal, Ahmct Tarik


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        "name": "Gurel, Busra"
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      {
        "affiliation": "Uludag Univ, Fac Med, Dept Pharmacol, Bursa, Turkey", 
        "name": "Cansev, Mehmet"
      }, 
      {
        "affiliation": "Uludag Univ, Fac Med, Dept Pharmacol, Bursa, Turkey", 
        "name": "Koc, Cansu"
      }, 
      {
        "affiliation": "Uludag Univ, Fac Med, Dept Physiol, Bursa, Turkey", 
        "name": "Ocalan, Busra"
      }, 
      {
        "affiliation": "Uludag Univ, Fac Med, Dept Physiol, Bursa, Turkey", 
        "name": "Cakir, Aysen"
      }, 
      {
        "affiliation": "Uludag Univ, Fac Med, Dept Pharmacol, Bursa, Turkey", 
        "name": "Aydin, Sami"
      }, 
      {
        "affiliation": "Uludag Univ, Fac Med, Dept Physiol, Bursa, Turkey", 
        "name": "Kahveci, Nevzat"
      }, 
      {
        "affiliation": "Acibadem Mehmet Ali Aydinlar Univ, Fac Med, Dept Pharmacol, Istanbul, Turkey", 
        "name": "Ulus, Ismail Hakki"
      }, 
      {
        "affiliation": "Acibadem Labmed R&D Lab, Istanbul, Turkey", 
        "name": "Sahin, Betul"
      }, 
      {
        "affiliation": "Acibadem Mehmet Ali Aydinlar Univ, Fac Med, Dept Med Biochem, Istanbul, Turkey", 
        "name": "Basar, Merve Karayel"
      }, 
      {
        "affiliation": "Acibadem Mehmet Ali Aydinlar Univ, Fac Med, Dept Med Biochem, Istanbul, Turkey", 
        "name": "Baykal, Ahmct Tarik"
      }
    ], 
    "description": "Background: CA1 subregion of the hippocampal formation is one of the primarily affected structures in AD, yet not much is known about proteome alterations in the extracellular milieu of this region. Objective: In this study, we aimed to identify the protein expression alterations throughout the pre-pathological, progression and pathological stages of AD mouse model.", 
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    "journal": {
      "issue": "7", 
      "pages": "613-621", 
      "title": "CURRENT ALZHEIMER RESEARCH", 
      "volume": "16"
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    "license": {
      "id": "cc-by"
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    "publication_date": "2019-01-01", 
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    "title": "Proteomics Analysis of CA1 Region of the Hippocampus in Pre-, Progression and Pathological Stages in a Mouse Model of the Alzheimer's Disease"
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