Dergi makalesi Açık Erişim

Proteomics Analysis of CA1 Region of the Hippocampus in Pre-, Progression and Pathological Stages in a Mouse Model of the Alzheimer's Disease

2019    Gurel, Busra; Cansev, Mehmet; Koc, Cansu; Ocalan, Busra; Cakir, Aysen; Aydin, Sami; Kahveci, Nevzat; Ulus, Ismail Hakki; Sahin, Betul; Basar, Merve Karayel; Baykal, Ahmct Tarik

Background: CA1 subregion of the hippocampal formation is one of the primarily affected structures in AD, yet not much is known about proteome alterations in the extracellular milieu of this region. Objective: In this study, we aimed to identify the protein expression alterations throughout the pre-pathological, progression and pathological stages of AD mouse model.