1 Ocak 2014 Dergi makalesi Açık Erişim

Ertas, Abdulselam; Goren, Ahmet Ceyhan; Boga, Mehmet; Demirci, Serpil; Kolak, Ufuk

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    "creators": [
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        "affiliation": "Dicle Univ, Fac Pharm, Dept Pharmacognosy, TR-21280 Diyarbakir, Turkey", 
        "name": "Ertas, Abdulselam"
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      {
        "affiliation": "Natl Metrol Inst, Chem Grp Labs, TUBITAK UME, TR-41470 Kocaeli, Turkey", 
        "name": "Goren, Ahmet Ceyhan"
      }, 
      {
        "affiliation": "Dicle Univ, Dept Pharmaceut Technol, Fac Pharm, TR-21280 Diyarbakir, Turkey", 
        "name": "Boga, Mehmet"
      }, 
      {
        "affiliation": "Cukurova Univ, Dept Pharmaceut Bot, Fac Pharm, TR-01330 Adana, Turkey", 
        "name": "Demirci, Serpil"
      }, 
      {
        "affiliation": "Istanbul Univ, Dept Gen & Analyt Chem, Fac Pharm, TR-34116 Istanbul, Turkey", 
        "name": "Kolak, Ufuk"
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    "description": "This report represents the first study on the chemical composition of essential oil of endemic Centaurea lycopifolia. This report also represents the first study on the anticholinesterase activity of essential oils of C. lycopifolia, C. balsamita and C. iberica. Essential oils were obtained using a Clevenger apparatus by hydrodistillation from the whole parts of C. lycopifolia, C. balsamita and C. iberica. The essential oils composition of the plants were determined by GC-FID and GC-MS (gas chromatograph/mass spectrometry) analysis. The major component of the essential oils was identified as caryophyllene oxide (9.7 %) and spathulenol (7.3 %) for C. lycopifolia, alpha-selinene (8.5 %) and hexatriacontane (8.3 %) for C. balsamita and arachidic acid (25.3 %) and hexadecanoic acid (5.9 %) for C. iberica. The essential oils of three Centaurea species indicated moderate inhibitory effect against butyrylcholinesterase and acetylcholinesterase enzyme, at 200 mu g/mL.", 
    "doi": "10.1080/0972060X.2014.886164", 
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    "journal": {
      "issue": "5", 
      "pages": "922-926", 
      "title": "JOURNAL OF ESSENTIAL OIL BEARING PLANTS", 
      "volume": "17"
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    "publication_date": "2014-01-01", 
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    "title": "Chemical Composition of The Essential Oils of Three Centaurea Species Growing Wild in Anatolia and Their Anticholinesterase Activities"
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