Dergi makalesi Açık Erişim

Determination of taxanes by validated LC-MS/MS method in hazelnut collected from different regions and altitudes in Turkey

Oguzkan, Sibel Bayil; Karagul, Bora; Aksoy, Elif Sine; Uzun, Ayse; Can, Merve; Yilmaz, Hasibe; Ugras, Halil Ibrahim; Binici, Burcu; Goren, Ahmet C.


DataCite XML

<?xml version='1.0' encoding='utf-8'?>
<resource xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://datacite.org/schema/kernel-4" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4.1/metadata.xsd">
  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/89875</identifier>
  <creators>
    <creator>
      <creatorName>Oguzkan, Sibel Bayil</creatorName>
      <givenName>Sibel Bayil</givenName>
      <familyName>Oguzkan</familyName>
      <affiliation>Gaziantep Univ, Arts &amp; Sci Fac, Biol Dept, Gaziantep, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karagul, Bora</creatorName>
      <givenName>Bora</givenName>
      <familyName>Karagul</familyName>
      <affiliation>Duzce Univ, Sci &amp; Arts Fac, Chem Dept Duzce, Duzce, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Aksoy, Elif Sine</creatorName>
      <givenName>Elif Sine</givenName>
      <familyName>Aksoy</familyName>
      <affiliation>Duzce Univ, Sci &amp; Arts Fac, Chem Dept Duzce, Duzce, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Uzun, Ayse</creatorName>
      <givenName>Ayse</givenName>
      <familyName>Uzun</familyName>
      <affiliation>Duzce Univ, Sci &amp; Arts Fac, Chem Dept Duzce, Duzce, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Can, Merve</creatorName>
      <givenName>Merve</givenName>
      <familyName>Can</familyName>
      <affiliation>Duzce Univ, Sci &amp; Arts Fac, Chem Dept Duzce, Duzce, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yilmaz, Hasibe</creatorName>
      <givenName>Hasibe</givenName>
      <familyName>Yilmaz</familyName>
      <affiliation>TUBITAK UME, Chem Grp, Organ Chem Lab, Gebze, Kocaeli, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ugras, Halil Ibrahim</creatorName>
      <givenName>Halil Ibrahim</givenName>
      <familyName>Ugras</familyName>
      <affiliation>Duzce Univ, Sci &amp; Arts Fac, Chem Dept Duzce, Duzce, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Binici, Burcu</creatorName>
      <givenName>Burcu</givenName>
      <familyName>Binici</familyName>
      <affiliation>TUBITAK UME, Chem Grp, Organ Chem Lab, Gebze, Kocaeli, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Goren, Ahmet C.</creatorName>
      <givenName>Ahmet C.</givenName>
      <familyName>Goren</familyName>
      <affiliation>TUBITAK UME, Chem Grp, Organ Chem Lab, Gebze, Kocaeli, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Determination Of Taxanes By Validated Lc-Ms/Ms Method In Hazelnut Collected From Different Regions And Altitudes In Turkey</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2018</publicationYear>
  <dates>
    <date dateType="Issued">2018-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/89875</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.25135/jcm.16.18.03.082</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">In this study, mass fractions of paclitaxel, cephalomannine, 10-DAB III and baccatin III in hazelnut were measured with new and validated LC-MS/MS method. Green outer nut husk and nutshell of Turkish hazelnut (Corylus colurna L.) were collected from Duzce, Trabzon, Adapazari and Samsun at several altitudes during August and September in 2014. The target analytes were prepared using solid-liquid extraction and analysed by LC-MS/MS. High amount of baccatin III, used for synthesizing semi-synthetic paclitaxel, was found in the nutshells collected at 250-500 m altitude in Cumayeri district of Duzce. In the husk samples from Vakfikebir district of Trabzon, the highest amount of baccatin III was obtained. The mass fractions of baccatin III in nutshell and husks were between 164.38-1020.85 mu gkg-1 and 166.12-923.64 mu gkg-1, respectively.</description>
  </descriptions>
</resource>
103
73
görüntülenme
indirilme
Görüntülenme 103
İndirme 73
Veri hacmi 49.7 MB
Tekil görüntülenme 93
Tekil indirme 66

Alıntı yap