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Chemical Constituents of Two Endemic Sideritis Species from Turkey with Antioxidant Activity

Carikci, Sema; Kilic, Turgut; Azizoglu, Akin; Topcu, Gulacti


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        "affiliation": "Balikesir Univ, Fac Arts & Sci, Dept Chem, TR-10145 Balikesir, Turkey", 
        "name": "Carikci, Sema"
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      {
        "affiliation": "Balikesir Univ, Fac Arts & Sci, Dept Chem, TR-10145 Balikesir, Turkey", 
        "name": "Kilic, Turgut"
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      {
        "affiliation": "Balikesir Univ, Fac Arts & Sci, Dept Chem, TR-10145 Balikesir, Turkey", 
        "name": "Azizoglu, Akin"
      }, 
      {
        "affiliation": "Bezmialem Vakif Univ, Fac Pharm, TR-34093 Fatih Istanbul, Turkey", 
        "name": "Topcu, Gulacti"
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    "description": "In this study, two Sideritis species, endemic to Turkey, S. niveotomentosa Huber - Morathii, S. brevidens P. H. Davis have been studied for their diterpenic compounds and the antioxidant properties. Eight known diterpenoids, which have ent-kaurene skeleton, were isolated from acetone and methanol extracts of these species. The structures of the isolated diterpenes were determined by using the NMR (H-1-NMR, C-13-NMR, COSY, HMQC, and HMBC) spectroscopy. The analysis of the phenolic compounds of the extracts was performed by high performance liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). Also the antioxidant capacity of the extracts was investigated namely by two methods; free radical scavenging and beta-carotene bleaching activities.", 
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