Dergi makalesi Açık Erişim
Guvenc-Bayram, Gokcen; Altinbas, Burcin; Erkan, Leman Gizem; Yalcin, Murat
<?xml version='1.0' encoding='UTF-8'?> <record xmlns="http://www.loc.gov/MARC21/slim"> <leader>00000nam##2200000uu#4500</leader> <datafield tag="700" ind1=" " ind2=" "> <subfield code="a">Altinbas, Burcin</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="a">Erkan, Leman Gizem</subfield> <subfield code="u">Bursa Uludag Univ, Fac Vet Med, Dept Physiol, TR-16059 Bursa, Turkey</subfield> </datafield> <datafield tag="700" ind1=" " ind2=" "> <subfield code="a">Yalcin, Murat</subfield> <subfield code="u">Bursa Uludag Univ, Fac Vet Med, Dept Physiol, TR-16059 Bursa, Turkey</subfield> </datafield> <datafield tag="909" ind1="C" ind2="4"> <subfield code="p">RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY</subfield> <subfield code="v">278</subfield> </datafield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="a">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="540" ind1=" " ind2=" "> <subfield code="a">Creative Commons Attribution</subfield> <subfield code="u">http://www.opendefinition.org/licenses/cc-by</subfield> </datafield> <datafield tag="024" ind1=" " ind2=" "> <subfield code="a">10.1016/j.resp.2020.103441</subfield> <subfield code="2">doi</subfield> </datafield> <datafield tag="245" ind1=" " ind2=" "> <subfield code="a">Modulation of arachidonic acid-evoked cardiorespiratory effects by the central lipoxygenase pathway</subfield> </datafield> <datafield tag="100" ind1=" " ind2=" "> <subfield code="a">Guvenc-Bayram, Gokcen</subfield> <subfield code="u">Bursa Uludag Univ, Fac Vet Med, Dept Physiol, TR-16059 Bursa, Turkey</subfield> </datafield> <datafield tag="909" ind1="C" ind2="O"> <subfield code="o">oai:zenodo.org:8499</subfield> <subfield code="p">user-tubitak-destekli-proje-yayinlari</subfield> </datafield> <datafield tag="650" ind1="1" ind2="7"> <subfield code="2">opendefinition.org</subfield> <subfield code="a">cc-by</subfield> </datafield> <datafield tag="260" ind1=" " ind2=" "> <subfield code="c">2020-01-01</subfield> </datafield> <datafield tag="856" ind1="4" ind2=" "> <subfield code="u">https://aperta.ulakbim.gov.trrecord/8499/files/bib-a2f13081-43e9-452a-9d6f-11248ab0d16a.txt</subfield> <subfield code="z">md5:da45b43c1af7578ec44a67b88f12ce06</subfield> <subfield code="s">214</subfield> </datafield> <datafield tag="542" ind1=" " ind2=" "> <subfield code="l">open</subfield> </datafield> <controlfield tag="005">20210315070037.0</controlfield> <controlfield tag="001">8499</controlfield> <datafield tag="980" ind1=" " ind2=" "> <subfield code="a">publication</subfield> <subfield code="b">article</subfield> </datafield> <datafield tag="520" ind1=" " ind2=" "> <subfield code="a">We previously reported that intracerebroventricularly (ICV) injected arachidonic acid (AA) could produce pressor and bradycardic responses on the cardiovascular system and hyperventilation effect on the respiratory system by activating cyclooxygenase (COX). We also demonstrated that centrally injected AA-induced cardiovascular and respiratory responses were mediated by COX-metabolites, such as thromboxane A(2) (TXA(2)), prostaglandin (PG) D, PGE, and PGF(2 alpha). Brain tissue is also able to express the lipoxygenase (LOX) enzyme and LOX-induced AA-metabolites. The current study was designed to investigate the possible mediation of the central LOX pathway in AA-induced cardiorespiratory effects in anesthetized rats.</subfield> </datafield> </record>
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