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Investigating Inhibitory Effects of Punica granatum Fruit Extracts on Lipid Peroxidation in the Fenton Reagent Environment

Ozsahin, Ayse Dilek; Kirecci, Oguz Ayhan; Yilmaz, Okkes; Erden, Yavuz; Bircan, Burak; Karaboga, Zeynep


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/84189</identifier>
  <creators>
    <creator>
      <creatorName>Ozsahin, Ayse Dilek</creatorName>
      <givenName>Ayse Dilek</givenName>
      <familyName>Ozsahin</familyName>
      <affiliation>Bitlis Eren Univ, Dept Biol, Fac Sci, TR-13000 Bitlis, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kirecci, Oguz Ayhan</creatorName>
      <givenName>Oguz Ayhan</givenName>
      <familyName>Kirecci</familyName>
      <affiliation>Inonu Univ, Dept Biol, Fac Sci, Malatya, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yilmaz, Okkes</creatorName>
      <givenName>Okkes</givenName>
      <familyName>Yilmaz</familyName>
      <affiliation>Firat Univ, Dept Biol, Fac Sci, TR-23169 Elazig, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Erden, Yavuz</creatorName>
      <givenName>Yavuz</givenName>
      <familyName>Erden</familyName>
      <affiliation>Firat Univ, Dept Biol, Fac Sci, TR-23169 Elazig, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Bircan, Burak</creatorName>
      <givenName>Burak</givenName>
      <familyName>Bircan</familyName>
      <affiliation>Firat Univ, Dept Biol, Fac Sci, TR-23169 Elazig, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karaboga, Zeynep</creatorName>
      <givenName>Zeynep</givenName>
      <familyName>Karaboga</familyName>
      <affiliation>Firat Univ, Dept Biol, Fac Sci, TR-23169 Elazig, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Investigating Inhibitory Effects Of Punica Granatum Fruit Extracts On Lipid Peroxidation In The Fenton Reagent Environment</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2012</publicationYear>
  <dates>
    <date dateType="Issued">2012-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/84189</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.81043/aperta.84188</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.81043/aperta.84189</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">In this study, it is aimed to find antioxidant activity of methanolic extract of Punica granatum fruit, by determining alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH) radical scavenging property and also by determining the capacity to prevent the formation of lipid peroxidation which is found in in-vitro environment that soybean and corn oils are found. The capacity of preventing lipid peroxidation was analyzed in an in vitro environment that oil samples were existed by evaporating methanol phase of extracts. In the experiment, the groups were formed as control group e.g., Fenton reactive, Pomegranate extract + Fenton reactive. It was observed that the lipid peroxidation level formed on the oils had increased at a significant level when compared to Fenton reactive groups according to the control group. When the extract groups are compared (to each other) according to the Fenton reactive group, it was detected that lipid peroxidation level had significantly decreased (p &amp;lt; 0.0001). According to the scavenging activity of alpha,alpha-diphenyl-beta-picrylhydrazyl radical, it was determined that the pomegranate extracts were effective at their highest level at 250-500 mu L (p &amp;lt; 0.0001). It was concluded that Punica granatum effectively decreases the lipid peroxidation level, neutralizes the alpha,alpha-diphenyl-beta-picrylhydrazyl free radical and has a characteristic of conserving the fatty acid content.</description>
  </descriptions>
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