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Biocompatible multi-walled carbon nanotube-CdTe quantum dot-polymer hybrids for medical applications

Baslak, Canan; Kars, Meltem Demirel; Karaman, Mustafa; Kus, Mahmut; Cengeloglu, Yunus; Ersoz, Mustafa


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{
  "DOI": "10.1016/j.jlumin.2014.11.030", 
  "abstract": "Herein we report the synthesis of polymer coated quantum dots (QDs)-carbon nanotube composite material with high biocompatibility and low cellular toxicity. The synthesized multi-walled carbon nanotube (MWCNT)-QD-(-poly(glycidyl methacrylate)) (pGMA) hybrids were characterized using X-ray photoelectron spectroscopy, laser scanning confocal microscopy, transmission electron microscopy and scanning electron microscopy. The results showed that quantum dots were well-distributed on nanotube surfaces in high density. The toxicological assessments of QDs and MWCNT-QD-polymer hybrids in human mammary carcinoma cells and their fluorescence imaging in living cell system were carried out. MWCNT-QD-polymer hybrids possess intense red fluorescence signal under confocal microscopy and good fluorescence stability over 6-h exposure in living cell system. The toxicity comparison of QDs and MWCNT-QD-polymer hybrids has shown that the existence of PGMA thin coating on MWCNT-QD hybrid surface decreased the cellular toxicity and increased biocompatibility. (C) 2014 Elsevier B.V. All rights reserved.", 
  "author": [
    {
      "family": "Baslak", 
      "given": " Canan"
    }, 
    {
      "family": "Kars", 
      "given": " Meltem Demirel"
    }, 
    {
      "family": "Karaman", 
      "given": " Mustafa"
    }, 
    {
      "family": "Kus", 
      "given": " Mahmut"
    }, 
    {
      "family": "Cengeloglu", 
      "given": " Yunus"
    }, 
    {
      "family": "Ersoz", 
      "given": " Mustafa"
    }
  ], 
  "container_title": "JOURNAL OF LUMINESCENCE", 
  "id": "80469", 
  "issued": {
    "date-parts": [
      [
        2015, 
        1, 
        1
      ]
    ]
  }, 
  "page": "9-15", 
  "title": "Biocompatible multi-walled carbon nanotube-CdTe quantum dot-polymer hybrids for medical applications", 
  "type": "article-journal", 
  "volume": "160"
}
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