1 Ocak 2015 Dergi makalesi Açık Erişim

Caglayan, Mehmet Gokhan; Torul, Hilal; Onur, Feyyaz; Tamer, Ugur

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/76685</identifier>
  <creators>
    <creator>
      <creatorName>Caglayan, Mehmet Gokhan</creatorName>
      <givenName>Mehmet Gokhan</givenName>
      <familyName>Caglayan</familyName>
      <affiliation>Ankara Univ, Fac Pharm, Dept Analyt Chem, TR-06100 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Torul, Hilal</creatorName>
      <givenName>Hilal</givenName>
      <familyName>Torul</familyName>
      <affiliation>Gazi Univ, Fac Pharm, Dept Analyt Chem, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Onur, Feyyaz</creatorName>
      <givenName>Feyyaz</givenName>
      <familyName>Onur</familyName>
      <affiliation>Ankara Univ, Fac Pharm, Dept Analyt Chem, TR-06100 Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tamer, Ugur</creatorName>
      <givenName>Ugur</givenName>
      <familyName>Tamer</familyName>
      <affiliation>Gazi Univ, Fac Pharm, Dept Analyt Chem, Ankara, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Sers-Based Assays For Sensitive Detection Of Modafinil</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2015</publicationYear>
  <dates>
    <date dateType="Issued">2015-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/76685</alternateIdentifier>
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  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1002/jrs.4722</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">In this paper, we proposed two sensitive surface-enhanced Raman spectroscopy assays for the determination of modafinil in urine matrix. In the first assay, modafinil was extracted by solid phase extraction and determined after sandwiching with silver nanoparticles. In the second assay, modafinil was extracted by non-specific interaction with magnetic gold nanoparticles and determined by sandwiching with magnetic gold and silver nanoparticles. The non-specific magnetic extraction does not require any analyte specific agent like antibody, aptamer, or molecularly imprinted polymer, therefore, the cost and complexity of the assay is very low. Both assays are capable for application to urine samples with the detection limits under the minimum required performance limit of modafinil. The assays were validated in terms of accuracy, precision, detection limits, and ranges. Copyright (C) 2015 John Wiley &amp;amp; Sons, Ltd.</description>
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