Dergi makalesi Açık Erişim

The prognostic significance of glutamic acid decarboxylase antibodies in patients with chronic pancreatitis undergoing total pancreatectomy with islet autotransplantation

2019    Kizilgul, M.; Wilhelm, J. J.; Dunn, T. B.; Beilman, G. J.; Pruett, T. L.; Chinnakotla, S.; Amin, K.; Hering, B. J.; Bellin, M. D.

Aim. - Islet autotransplantation (IAT) is considered a 'non-immune' model of islet transplant, with no risk for autoimmune-mediated beta cell loss, but we have previously observed de novo type 1 diabetes in one total pancreatectomy with islet autotransplantation (TPIAT) recipient. We aimed to investigate the clinical significance of glutamic acid decarboxylase antibodies (GADA), as a sensitive marker for autoimmune diabetes mellitus (DM), in patients with chronic pancreatitis undergoing TPIAT.