1 Ocak 2020 Dergi makalesi Açık Erişim

Seven, Fikri; Golcez, Tansu; Yarali, Ziysan Buse; Onak, Gunnur; Karaman, Ozan; Sen, Mustafa

DataCite XML

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/7549</identifier>
  <creators>
    <creator>
      <creatorName>Seven, Fikri</creatorName>
      <givenName>Fikri</givenName>
      <familyName>Seven</familyName>
      <affiliation>Izmir Katip Celebi Univ, Grad Sch Nat &amp; Appl Sci, Dept Biomed Technol, Sci, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Golcez, Tansu</creatorName>
      <givenName>Tansu</givenName>
      <familyName>Golcez</familyName>
      <affiliation>Izmir Katip Celebi Univ, Grad Sch Nat &amp; Appl Sci, Dept Biomed Technol, Sci, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yarali, Ziysan Buse</creatorName>
      <givenName>Ziysan Buse</givenName>
      <familyName>Yarali</familyName>
      <affiliation>Izmir Katip Celebi Univ, Grad Sch Nat &amp; Appl Sci, Biomed Test Calibrat Applicat &amp; Res Ctr, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Onak, Gunnur</creatorName>
      <givenName>Gunnur</givenName>
      <familyName>Onak</familyName>
      <affiliation>Izmir Katip Celebi Univ, Grad Sch Nat &amp; Appl Sci, Biomed Test Calibrat Applicat &amp; Res Ctr, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karaman, Ozan</creatorName>
      <givenName>Ozan</givenName>
      <familyName>Karaman</familyName>
      <affiliation>Izmir Katip Celebi Univ, Fac Engn &amp; Architecture, Biomed Engn, Izmir, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Sen, Mustafa</creatorName>
      <givenName>Mustafa</givenName>
      <familyName>Sen</familyName>
      <affiliation>Izmir Katip Celebi Univ, Fac Engn &amp; Architecture, Biomed Engn, Izmir, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Guiding Neural Extensions Of Pc12 Cells On Carbon Nanotube Tracks Dielectrophoretically Formed In Poly(Ethylene Glycol) Dimethacrylate</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2020</publicationYear>
  <dates>
    <date dateType="Issued">2020-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/7549</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1039/d0ra04496b</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">The PC12 cell line has been widely used as anin vitromodel for studying neuronal differentiation and identifying the factors affecting the process. It has the ability to differentiate in the presence of nerve growth factor (NGF), resulting in neural extensions called dendrites and axons. In this study, first the impact of randomly distributed multi-walled carbon nanotubes (MWCNTs) in poly(ethylene glycol) dimethacrylate (PEGDMA) on PC12 cell differentiation was investigated in terms of neurite length, number of neurite per cell and differentiation marker gene expression profile. Then, dielectrophoretically aligned MWCNTs in PEGDMA was used to guide and support the neuronal differentiation of PC12 cells in the presence of NGF. The method is expected to be useful in revealing the nanotopographical role in fundamental studies and understanding of nanotopographical effects for biomedical applications on nerve regeneration.</description>
  </descriptions>
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