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In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey

Keser, Serhat; Keser, Fatma; Turkoglu, Ismail; Kaygili, Omer; Tekin, Suat; Demir, Ersin; Karatepe, Mustafa; Yilmaz, Okkes; Kirbag, Sevda; Sandal, Suleyman; Turkoglu, Semra


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/7471</identifier>
  <creators>
    <creator>
      <creatorName>Keser, Serhat</creatorName>
      <givenName>Serhat</givenName>
      <familyName>Keser</familyName>
      <affiliation>Firat Univ, Fac Sci, Dept Chem, Elazig 23119, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Keser, Fatma</creatorName>
      <givenName>Fatma</givenName>
      <familyName>Keser</familyName>
      <affiliation>Firat Univ, Fac Sci, Dept Chem, Elazig 23119, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Turkoglu, Ismail</creatorName>
      <givenName>Ismail</givenName>
      <familyName>Turkoglu</familyName>
      <affiliation>Firat Univ, Fac Educ, Dept Biol Educ, Elazig 23119, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kaygili, Omer</creatorName>
      <givenName>Omer</givenName>
      <familyName>Kaygili</familyName>
      <affiliation>Firat Univ, Fac Sci, Dept Phys, Elazig 23119, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Tekin, Suat</creatorName>
      <givenName>Suat</givenName>
      <familyName>Tekin</familyName>
      <affiliation>Inonu Univ, Fac Med, Dept Physiol, Malatya 44000, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Demir, Ersin</creatorName>
      <givenName>Ersin</givenName>
      <familyName>Demir</familyName>
      <affiliation>Duzce Univ, Agr &amp; Nat Sci Fac, Dept Agr Biotechnol, Duzce 81000, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Karatepe, Mustafa</creatorName>
      <givenName>Mustafa</givenName>
      <familyName>Karatepe</familyName>
      <affiliation>Firat Univ, Fac Sci, Dept Chem, Elazig 23119, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Yilmaz, Okkes</creatorName>
      <givenName>Okkes</givenName>
      <familyName>Yilmaz</familyName>
      <affiliation>Firat Univ, Fac Sci, Dept Biol, Elazig 23119, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Kirbag, Sevda</creatorName>
      <givenName>Sevda</givenName>
      <familyName>Kirbag</familyName>
      <affiliation>Firat Univ, Fac Sci, Dept Biol, Elazig 23119, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Sandal, Suleyman</creatorName>
      <givenName>Suleyman</givenName>
      <familyName>Sandal</familyName>
      <affiliation>Inonu Univ, Fac Med, Dept Physiol, Malatya 44000, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Turkoglu, Semra</creatorName>
      <givenName>Semra</givenName>
      <familyName>Turkoglu</familyName>
      <affiliation>Firat Univ, Fac Hlth Sci, Dept Nutr &amp; Dietet, Elazig 23119, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>In Vitro Biological Evaluation And Phytochemical Contents Of Three Centaurea L. Species Growing From Eastern Anatolia In Turkey</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2020</publicationYear>
  <dates>
    <date dateType="Issued">2020-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/7471</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.18016/ksutarimdoga.vi.589279</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Centaurea L. species were used as medicinal plants among the people for treatment of the common cold, abscesses, peptic ulcers, hemorrhoid and diabetes etc.. In the present study, antiradical properties, phytochemical contents, antimicrobial and antiproliferative activities of three Centaurea species were investigated. Centaurea saligna (K.Koch) Wagenitz methanol (99.94%), Centaurea virgata Lam. methanol (98.23%) and water (98.10%) extracts were showed higher ABTS scavenging than trolox (96.79%). Centaurea kurdica Reichardt extracts showed lower activity than trolox for all the antiradical assays. Centaurea extracts exhibited antimicrobial activity against to some microorganisms. It was determined that these Centaurea species contain high amount of total flavonoid, phenolic and proanthocyanidin, phenolic acids, phytosterols and unsaturated fatty acids. Also, three Centaurea extracts showed very high antiproliferative property on LNCaP, HCT-116, MCF-7 cancer cell lines.</description>
  </descriptions>
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