1 Ocak 2019 Dergi makalesi Açık Erişim

Konuklugil, Belma; Sertdemir, Melek; Heydari, Hajar; Koc, Asli

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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/74183</identifier>
  <creators>
    <creator>
      <creatorName>Konuklugil, Belma</creatorName>
      <givenName>Belma</givenName>
      <familyName>Konuklugil</familyName>
      <affiliation>Ankara Univ, Fac Pharm, Pharmacognosy Dept, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Sertdemir, Melek</creatorName>
      <givenName>Melek</givenName>
      <familyName>Sertdemir</familyName>
      <affiliation>Ankara Univ, Biotechnol Inst, Basic Biotechnol, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Heydari, Hajar</creatorName>
      <givenName>Hajar</givenName>
      <familyName>Heydari</familyName>
      <affiliation>Ankara Univ, Fac Pharm, Pharmacognosy Dept, Ankara, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Koc, Asli</creatorName>
      <givenName>Asli</givenName>
      <familyName>Koc</familyName>
      <affiliation>Ankara Univ, Fac Pharm, Biochem Dept, Ankara, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Isolation And Bioactivities Screening Of Turkish Microcosmus Vulgaris</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2019</publicationYear>
  <dates>
    <date dateType="Issued">2019-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/74183</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.4194/1303-2712-v19_8_03</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">During the course of our investigation for isolation of biological active compounds from marine organisms of the Turkish seas, secondary metabolites and bioactivities of, Microcosmus vulgaris collected from (Turkish coasts) Izmir coast was studied. In the study 5 alpha - 6 alpha - epoxyergosta 7-en- 3 beta- ol was isolated from Microcosmus vulgaris. Furthermore, antioxidant and antiproliferative activity of crude extract and 5 alpha- 6 alpha-epoxyergosta 7-en- 3 beta- ol were determined by DPPH, superoxide radical scavenging and nitric oxide radical scavenging and MTT assay respectively. Antimicrobial activity of crude extract was also determined against some Gram positive, Gram negative and yeast strains. Stearic acid, palmitic acid and myristic acid were also detected by GC-MASS analysis. This is the first study about isolation and bioactivity determination of Turkish M. vulgaris.</description>
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