1 Ocak 2019 Dergi makalesi Açık Erişim

Mermer, Arif; Bayrak, Hacer; Sirin, Yakup; Emirik, Mustafa; Demirbas, Neslihan

JSON

{
  "conceptrecid": "74084", 
  "created": "2021-03-16T04:06:52.008116+00:00", 
  "doi": "10.1016/j.molstruc.2019.04.039", 
  "files": [
    {
      "bucket": "35df1572-201a-4cf6-b5b8-2bc6d053322c", 
      "checksum": "md5:cd85bce2408daef58b101a5207b50fe4", 
      "key": "bib-6b8941c5-80b5-4b39-907d-546693d4aa25.txt", 
      "links": {
        "self": "https://aperta.ulakbim.gov.tr/api/files/35df1572-201a-4cf6-b5b8-2bc6d053322c/bib-6b8941c5-80b5-4b39-907d-546693d4aa25.txt"
      }, 
      "size": 321, 
      "type": "txt"
    }
  ], 
  "id": 74085, 
  "links": {
    "badge": "https://aperta.ulakbim.gov.tr/badge/doi/10.1016/j.molstruc.2019.04.039.svg", 
    "bucket": "https://aperta.ulakbim.gov.tr/api/files/35df1572-201a-4cf6-b5b8-2bc6d053322c", 
    "doi": "https://doi.org/10.1016/j.molstruc.2019.04.039", 
    "html": "https://aperta.ulakbim.gov.tr/record/74085", 
    "latest": "https://aperta.ulakbim.gov.tr/api/records/74085", 
    "latest_html": "https://aperta.ulakbim.gov.tr/record/74085"
  }, 
  "metadata": {
    "access_right": "open", 
    "access_right_category": "success", 
    "communities": [
      {
        "id": "tubitak-destekli-proje-yayinlari"
      }
    ], 
    "creators": [
      {
        "affiliation": "Karadeniz Tech Univ, Dept Chem, TR-61080 Trabzon, Turkey", 
        "name": "Mermer, Arif"
      }, 
      {
        "affiliation": "Karadeniz Tech Univ, Dept Chem & Chem Proc Technol, TR-61080 Trabzon, Turkey", 
        "name": "Bayrak, Hacer"
      }, 
      {
        "affiliation": "Karadeniz Tech Univ, Dept Chem, TR-61080 Trabzon, Turkey", 
        "name": "Sirin, Yakup"
      }, 
      {
        "affiliation": "Recep Tayyip Erdogan Univ, Dept Chem, TR-53100 Rize, Turkey", 
        "name": "Emirik, Mustafa"
      }, 
      {
        "affiliation": "Karadeniz Tech Univ, Dept Chem, TR-61080 Trabzon, Turkey", 
        "name": "Demirbas, Neslihan"
      }
    ], 
    "description": "This study reports the synthesis, biological investigation and molecular docking of novel beta-lactam derivatives bearing 1,3,4-thiadiazole and 1,3,4-oxadiazole ring system. The synthesized compounds were evaluated for in vitro antiurease activity and antioxidant capacity. Almost all compounds showed excellent antiurease activity compared to thiourea, standard drug. Also, in silico ADME (absorption, distribution, metabolism, elimination) prediction and molecular docking studies were performed. (C) 2019 Elsevier B.V. All rights reserved.", 
    "doi": "10.1016/j.molstruc.2019.04.039", 
    "has_grant": false, 
    "journal": {
      "pages": "279-287", 
      "title": "JOURNAL OF MOLECULAR STRUCTURE", 
      "volume": "1189"
    }, 
    "license": {
      "id": "cc-by"
    }, 
    "publication_date": "2019-01-01", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "74085"
          }, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "74084"
          }
        }
      ]
    }, 
    "resource_type": {
      "subtype": "article", 
      "title": "Dergi makalesi", 
      "type": "publication"
    }, 
    "title": "Synthesis of novel Azol-beta-lactam derivatives starting from phenyl piperazine and investigation of their antiurease activity and antioxidant capacity comparing with their molecular docking studies"
  }, 
  "owners": [
    1
  ], 
  "revision": 1, 
  "stats": {
    "downloads": 3.0, 
    "unique_downloads": 3.0, 
    "unique_views": 11.0, 
    "version_downloads": 3.0, 
    "version_unique_downloads": 3.0, 
    "version_unique_views": 11.0, 
    "version_views": 12.0, 
    "version_volume": 963.0, 
    "views": 12.0, 
    "volume": 963.0
  }, 
  "updated": "2021-03-16T04:06:52.056470+00:00"
}