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Biological activity of new flavonoids and phenolic compounds from Cirsium italicum (Savi) DC.

Sabudak, Temine; Caliskan, Hilmican; Orak, H. Hulya; Ozer, Merve


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  <identifier identifierType="URL">https://aperta.ulakbim.gov.tr/record/70733</identifier>
  <creators>
    <creator>
      <creatorName>Sabudak, Temine</creatorName>
      <givenName>Temine</givenName>
      <familyName>Sabudak</familyName>
      <affiliation>Namik Kemal Univ, Fac Sci &amp; Arts, Dept Chem, Tekirdag, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Caliskan, Hilmican</creatorName>
      <givenName>Hilmican</givenName>
      <familyName>Caliskan</familyName>
      <affiliation>Namik Kemal Univ, Fac Sci &amp; Arts, Dept Chem, Tekirdag, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Orak, H. Hulya</creatorName>
      <givenName>H. Hulya</givenName>
      <familyName>Orak</familyName>
      <affiliation>Namik Kemal Univ, Vocat Sch Tech Sci, Dept Food Technol, Tekirdag, Turkey</affiliation>
    </creator>
    <creator>
      <creatorName>Ozer, Merve</creatorName>
      <givenName>Merve</givenName>
      <familyName>Ozer</familyName>
      <affiliation>Namik Kemal Univ, Fac Sci &amp; Arts, Dept Chem, Tekirdag, Turkey</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Biological Activity Of New Flavonoids And Phenolic Compounds From Cirsium Italicum (Savi) Dc.</title>
  </titles>
  <publisher>Aperta</publisher>
  <publicationYear>2019</publicationYear>
  <dates>
    <date dateType="Issued">2019-01-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://aperta.ulakbim.gov.tr/record/70733</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1080/14786419.2019.1630121</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="http://www.opendefinition.org/licenses/cc-by">Creative Commons Attribution</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Cirsium italicum (Savi) DC. was researched for its phytochemicals for the first time. Two new biflavonoids, 5,5'',7''-trihydroxy-3,7-dimethoxy-4'-4'''-O-biflavone (3), (8,3',4',5'-tetrahydroxy-7-O-alpha-glucosyl isoflavone)-6-8''-(4'''-hydroxy-7''-O-alpha-glucosyl isoflavone) biflavone (7), a new isoflavone, 6-2'-dihydroxy-5-methoxy isoflavonone-4'-O-alpha-D-glucopyranoside (5) and a new phenolic compound, ethyl-(2,3-dihydroxy-5,6-dimethoxy-4-acetyl) benzoate (4), together with three known compounds (1), (2) and (6) were isolated from Cirsium italicum. Their structures were elucidated by extensive 1D and 2D NMR, and MS data analyses. All compounds isolated from C. italicum exhibited antioxidant activity. However, the highest activity of the EtOAc extract is considered to be responsible for compounds (1), (2) and (3) being the main compounds.</description>
  </descriptions>
</resource>
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